3q0c

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[[Image:3q0c.jpg|left|200px]]
 
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{{STRUCTURE_3q0c| PDB=3q0c | SCENE= }}
{{STRUCTURE_3q0c| PDB=3q0c | SCENE= }}
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===Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122===
===Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122===
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{{ABSTRACT_PUBMED_21245167}}
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==Function==
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[[http://www.uniprot.org/uniprot/SUVH5_ARATH SUVH5_ARATH]] Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.
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(as it appears on PubMed at http://www.pubmed.gov), where 21245167 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21245167}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21245167</ref><references group="xtra"/>
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<ref group="xtra">PMID:021245167</ref><references group="xtra"/><references/>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Histone-lysine N-methyltransferase]]
[[Category: Histone-lysine N-methyltransferase]]
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[[Category: Patel, D J.]]
[[Category: Patel, D J.]]
[[Category: Simanshu, D K.]]
[[Category: Simanshu, D K.]]
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[[Category: 5mc binding protein]]
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[[Category: Fully methylated cg]]
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[[Category: Fully methylated cg dna duplex]]
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[[Category: Sra]]
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[[Category: Suvh5]]
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[[Category: Transferase-dna complex]]

Revision as of 08:33, 8 May 2013

Template:STRUCTURE 3q0c

Contents

Crystal structure of SUVH5 SRA-fully methylated CG DNA complex in space group P6122

Template:ABSTRACT PUBMED 21245167

Function

[SUVH5_ARATH] Histone methyltransferase. Methylates 'Lys-9' of histone H3. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression.

About this Structure

3q0c is a 4 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

  • Rajakumara E, Law JA, Simanshu DK, Voigt P, Johnson LM, Reinberg D, Patel DJ, Jacobsen SE. A dual flip-out mechanism for 5mC recognition by the Arabidopsis SUVH5 SRA domain and its impact on DNA methylation and H3K9 dimethylation in vivo. Genes Dev. 2011 Jan 15;25(2):137-52. PMID:21245167 doi:10.1101/gad.1980311

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OCA

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