Peroxiredoxin
From Proteopedia
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[[2i81]] - 2Cys-Prx – ''Plasmodium vivax''<br /> | [[2i81]] - 2Cys-Prx – ''Plasmodium vivax''<br /> | ||
[[1qmv]] - h2Cys-Prx – human<br /> | [[1qmv]] - h2Cys-Prx – human<br /> | ||
| + | [[2a4v]] – yPrx dot5 C-termianl (mutant) – yeast<br /> | ||
| + | [[3cmi]] – yPrx hyr1<br /> | ||
| + | [[4g2e]] – Prx – ''Sulfolobus tokodaii''<br /> | ||
| + | [[3sbc]] – yPrx Tsa1 (mutant)<br /> | ||
| + | [[1uul]] - 2Cys-Prx – ''Trypanosoma cruzi''<br /> | ||
| + | [[1we0]] – Prx – ''Amphibacillus xylanus''<br /> | ||
| + | [[2cv4]], [[2cx3]], [[2cx4]] – Prx – ''Aeropyrum pernix''<br /> | ||
| + | [[3drn]] – SsPrx – ''Sulfolobus solfataricus''<br /> | ||
| + | [[3hjp]] – SsPrx (mutant)<br /> | ||
| + | [[3ixr]] – Prx PRXQ (mutant) – ''Xylella fastidiosa''<br /> | ||
| + | |||
| + | ===Peroxiredoxin 1=== | ||
| + | |||
[[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br /> | [[2rii]], [[3hy2]] – hPrx 1 (mutant)+sulfiredoxin 1<br /> | ||
[[2z9s]] – Prx 1 (mutant) - rat<br /> | [[2z9s]] – Prx 1 (mutant) - rat<br /> | ||
| + | |||
| + | ===Peroxiredoxin 2=== | ||
| + | |||
| + | [[1tp9]] – Prx II – ''Populus trichocarpa''<br /> | ||
| + | [[2pwj]] – Prx II – garden pea<br /> | ||
| + | [[4dsq]], [[4dsr]], [[4h86]] – yPrx II<br /> | ||
| + | [[4dss]] – yPrx II (mutant) + thioredoxin II<br /> | ||
| + | |||
| + | ===Peroxiredoxin 3=== | ||
| + | |||
| + | [[1zye]] – Prx III (mutant) – bovine<br /> | ||
| + | |||
| + | ===Peroxiredoxin 4=== | ||
| + | |||
[[3tjf]], [[3tjg]], [[3tjj]], [[3tjk]], [[3tkr]] - hPrx 4 (mutant)<br /> | [[3tjf]], [[3tjg]], [[3tjj]], [[3tjk]], [[3tkr]] - hPrx 4 (mutant)<br /> | ||
[[3qpm]] – Prx 4 – ''Larimichtys crocea''<br /> | [[3qpm]] – Prx 4 – ''Larimichtys crocea''<br /> | ||
[[2pn8]], [[3tjb]], [[3tkp]], [[3tkq]], [[3tks]] – hPrx 4<br /> | [[2pn8]], [[3tjb]], [[3tkp]], [[3tkq]], [[3tks]] – hPrx 4<br /> | ||
| + | |||
| + | ===Peroxiredoxin 5=== | ||
| + | |||
[[1urm]] – hPrx 5 (mutant) – human<br /> | [[1urm]] – hPrx 5 (mutant) – human<br /> | ||
[[2vl2]], [[2vl3]], [[2vl9]], [[1h4o]], [[1hd2]], [[1oc3]] – hPrx 5<br /> | [[2vl2]], [[2vl3]], [[2vl9]], [[1h4o]], [[1hd2]], [[1oc3]] – hPrx 5<br /> | ||
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[[2wfc]] – lPrx 5 - lugworm<br /> | [[2wfc]] – lPrx 5 - lugworm<br /> | ||
[[2xhf]] – Prx 5 – ''Alvinella pompejana''<br /> | [[2xhf]] – Prx 5 – ''Alvinella pompejana''<br /> | ||
| + | |||
| + | ===Peroxiredoxin 6=== | ||
| + | |||
[[2v2g]] – lPrx 6 <br /> | [[2v2g]] – lPrx 6 <br /> | ||
[[2v32]], [[2v41]] – lPrx 6 (mutant)<br /> | [[2v32]], [[2v41]] – lPrx 6 (mutant)<br /> | ||
| - | [[2a4v]] – yPrx dot5 C-termianl (mutant) – yeast<br /> | ||
| - | [[3cmi]] – yPrx hyr1<br /> | ||
| - | [[1tp9]] – Prx II – ''Populus trichocarpa''<br /> | ||
| - | [[2pwj]] – Prx II – garden pea<br /> | ||
| - | [[4g2e]] – Prx – ''Sulfolobus tokodaii''<br /> | ||
| - | [[4dsq]], [[4dsr]], [[4h86]] – yPrx II<br /> | ||
| - | [[3sbc]] – yPrx Tsa1 (mutant)<br /> | ||
| - | [[4dss]] – yPrx II (mutant) + thioredoxin II<br /> | ||
| - | [[1uul]] - 2Cys-Prx – ''Trypanosoma cruzi''<br /> | ||
| - | [[1we0]] – Prx – ''Amphibacillus xylanus''<br /> | ||
| - | [[1zye]] – Prx III (mutant) – bovine<br /> | ||
| - | [[2cv4]], [[2cx3]], [[2cx4]] – Prx – ''Aeropyrum pernix''<br /> | ||
| - | [[3drn]] – SsPrx – ''Sulfolobus solfataricus''<br /> | ||
| - | [[3hjp]] – SsPrx (mutant)<br /> | ||
| - | [[3ixr]] – Prx PRXQ (mutant) – ''Xylella fastidiosa''<br /> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 12:24, 14 May 2013
Peroxiredoxin (Prx) is an antioxidant enzyme. In the Prxs the active-site Cys is oxidized to sulfenic acid byperoxide. The Prxs are divided into typical 2-Cys Prx, atypical 2-Cys Prx and 1-Cys Prx. Prx 5 is expressed in mammalian tissue. The images at the left and at the right correspond to one representative Prx, i.e. the crystal structure of Peroxiredoxin from rat (1qq2).
Contents |
3D Structures of Peroxiredoxin
Updated February 2013
1qq2 – 2Cys-Prx – rat
2c0d – Pf2Cys-Prx – Plasmodium falciparum
1xiy – Pf1Cys-Prx
1xcc, 2h01, 3tb2 - 1Cys-Prx – Plasmodium yoelii
2i81 - 2Cys-Prx – Plasmodium vivax
1qmv - h2Cys-Prx – human
2a4v – yPrx dot5 C-termianl (mutant) – yeast
3cmi – yPrx hyr1
4g2e – Prx – Sulfolobus tokodaii
3sbc – yPrx Tsa1 (mutant)
1uul - 2Cys-Prx – Trypanosoma cruzi
1we0 – Prx – Amphibacillus xylanus
2cv4, 2cx3, 2cx4 – Prx – Aeropyrum pernix
3drn – SsPrx – Sulfolobus solfataricus
3hjp – SsPrx (mutant)
3ixr – Prx PRXQ (mutant) – Xylella fastidiosa
Peroxiredoxin 1
2rii, 3hy2 – hPrx 1 (mutant)+sulfiredoxin 1
2z9s – Prx 1 (mutant) - rat
Peroxiredoxin 2
1tp9 – Prx II – Populus trichocarpa
2pwj – Prx II – garden pea
4dsq, 4dsr, 4h86 – yPrx II
4dss – yPrx II (mutant) + thioredoxin II
Peroxiredoxin 3
1zye – Prx III (mutant) – bovine
Peroxiredoxin 4
3tjf, 3tjg, 3tjj, 3tjk, 3tkr - hPrx 4 (mutant)
3qpm – Prx 4 – Larimichtys crocea
2pn8, 3tjb, 3tkp, 3tkq, 3tks – hPrx 4
Peroxiredoxin 5
1urm – hPrx 5 (mutant) – human
2vl2, 2vl3, 2vl9, 1h4o, 1hd2, 1oc3 – hPrx 5
3mng – hPrx 5+DTT
2wfc – lPrx 5 - lugworm
2xhf – Prx 5 – Alvinella pompejana
Peroxiredoxin 6
2v2g – lPrx 6
2v32, 2v41 – lPrx 6 (mutant)
