2yoa

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m (Protected "2yoa" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_2yoa| PDB=2yoa | SCENE= }}
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===Synaptotagmin-1 C2B domain with phosphoserine===
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The entry 2yoa is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/SYT1_RAT SYT1_RAT]] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.
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Authors: Honigmann, A., van den Bogaart, G., Iraheta, E., Risselada, H.J., Milovanovic, D., Mueller, V., Muellar, S., Diederichsen, U., Fasshauer, D., Grubmuller, H., Hell, S.W., Eggeling, C., Kuhnel, K., Jahn, R.
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==About this Structure==
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[[2yoa]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YOA OCA].
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Description: Synaptotagmin-1 C2B domain with phosphoserine
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[[Category: Rattus norvegicus]]
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[[Category: Bogaart, G van den.]]
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[[Category: Diederichsen, U.]]
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[[Category: Eggeling, C.]]
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[[Category: Fasshauer, D.]]
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[[Category: Grubmuller, H.]]
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[[Category: Hell, S W.]]
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[[Category: Honigmann, A.]]
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[[Category: Iraheta, E.]]
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[[Category: Jahn, R.]]
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[[Category: Kuhnel, K.]]
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[[Category: Milovanovic, D.]]
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[[Category: Muellar, S.]]
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[[Category: Mueller, V.]]
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[[Category: Risselada, H J.]]
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[[Category: Signaling protein]]

Revision as of 06:07, 16 May 2013

Template:STRUCTURE 2yoa

Synaptotagmin-1 C2B domain with phosphoserine

Function

[SYT1_RAT] May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2.

About this Structure

2yoa is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

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