3kfu
From Proteopedia
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| - | [[Image:3kfu.png|left|200px]] | ||
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{{STRUCTURE_3kfu| PDB=3kfu | SCENE= }} | {{STRUCTURE_3kfu| PDB=3kfu | SCENE= }} | ||
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===Crystal structure of the transamidosome=== | ===Crystal structure of the transamidosome=== | ||
| + | {{ABSTRACT_PUBMED_20717102}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/GATC_THET8 GATC_THET8]] Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity). [[http://www.uniprot.org/uniprot/GATB_THET8 GATB_THET8]] Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln). [[http://www.uniprot.org/uniprot/GATA_THET8 GATA_THET8]] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Also acts on Asp-tRNA(Asn). | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3kfu]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3kfu]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFU OCA]. |
==See Also== | ==See Also== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:020717102</ref><references group="xtra"/> | + | <ref group="xtra">PMID:020717102</ref><references group="xtra"/><references/> |
| - | [[Category: Thermus thermophilus]] | + | [[Category: Thermus thermophilus hb8]] |
[[Category: Bailly, M.]] | [[Category: Bailly, M.]] | ||
[[Category: Becker, H D.]] | [[Category: Becker, H D.]] | ||
Revision as of 06:26, 16 May 2013
Contents |
Crystal structure of the transamidosome
Template:ABSTRACT PUBMED 20717102
Function
[GATC_THET8] Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity). [GATB_THET8] Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln). [GATA_THET8] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Also acts on Asp-tRNA(Asn).
About this Structure
3kfu is a 14 chain structure with sequence from Thermus thermophilus hb8. Full crystallographic information is available from OCA.
See Also
Reference
- Blaise M, Bailly M, Frechin M, Behrens MA, Fischer F, Oliveira CL, Becker HD, Pedersen JS, Thirup S, Kern D. Crystal structure of a transfer-ribonucleoprotein particle that promotes asparagine formation. EMBO J. 2010 Sep 15;29(18):3118-29. Epub 2010 Aug 17. PMID:20717102 doi:10.1038/emboj.2010.192
