This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3kfu
From Proteopedia
| Line 1: | Line 1: | ||
| - | [[Image:3kfu.png|left|200px]] | ||
| - | |||
{{STRUCTURE_3kfu| PDB=3kfu | SCENE= }} | {{STRUCTURE_3kfu| PDB=3kfu | SCENE= }} | ||
| - | |||
===Crystal structure of the transamidosome=== | ===Crystal structure of the transamidosome=== | ||
| + | {{ABSTRACT_PUBMED_20717102}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/GATC_THET8 GATC_THET8]] Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity). [[http://www.uniprot.org/uniprot/GATB_THET8 GATB_THET8]] Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln). [[http://www.uniprot.org/uniprot/GATA_THET8 GATA_THET8]] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Also acts on Asp-tRNA(Asn). | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3kfu]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3kfu]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KFU OCA]. |
==See Also== | ==See Also== | ||
| Line 14: | Line 13: | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:020717102</ref><references group="xtra"/> | + | <ref group="xtra">PMID:020717102</ref><references group="xtra"/><references/> |
| - | [[Category: Thermus thermophilus]] | + | [[Category: Thermus thermophilus hb8]] |
[[Category: Bailly, M.]] | [[Category: Bailly, M.]] | ||
[[Category: Becker, H D.]] | [[Category: Becker, H D.]] | ||
Revision as of 06:26, 16 May 2013
Contents |
Crystal structure of the transamidosome
Template:ABSTRACT PUBMED 20717102
Function
[GATC_THET8] Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity). [GATB_THET8] Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln). [GATA_THET8] Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Also acts on Asp-tRNA(Asn).
About this Structure
3kfu is a 14 chain structure with sequence from Thermus thermophilus hb8. Full crystallographic information is available from OCA.
See Also
Reference
- Blaise M, Bailly M, Frechin M, Behrens MA, Fischer F, Oliveira CL, Becker HD, Pedersen JS, Thirup S, Kern D. Crystal structure of a transfer-ribonucleoprotein particle that promotes asparagine formation. EMBO J. 2010 Sep 15;29(18):3118-29. Epub 2010 Aug 17. PMID:20717102 doi:10.1038/emboj.2010.192
