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4f37

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4f37| PDB=4f37 | SCENE= }}
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===Structure of the tethered N-terminus of Alzheimer's disease A peptide===
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{{ABSTRACT_PUBMED_23609990}}
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The entry 4f37 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/IMM7_ECOLX IMM7_ECOLX]] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.
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Authors: Nisbet, R.N., Nuttall, S.D., Caine, J.M., Rober, R., Hittaki, M., Pearce, L.A., Davydova, N., Masters, C.L., Varghese, J.N., Streltsov, V.A.
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==About this Structure==
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[[4f37]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F37 OCA].
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Description: Structure of the tethered N-terminus of Alzheimer's disease A peptide
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[[Category: Escherichia coli]]
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[[Category: Mus musculus]]
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[[Category: Caine, J M.]]
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[[Category: Davydova, N.]]
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[[Category: Hittaki, M.]]
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[[Category: Masters, C L.]]
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[[Category: Nisbet, R M.]]
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[[Category: Nuttall, S D.]]
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[[Category: Pearce, L A.]]
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[[Category: Rober, R.]]
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[[Category: Streltsov, V A.]]
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[[Category: Varghese, J N.]]
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[[Category: Alzheimer's disease]]
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[[Category: Amyloid-beta]]
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[[Category: Immune system]]

Revision as of 07:16, 16 May 2013

Template:STRUCTURE 4f37

Structure of the tethered N-terminus of Alzheimer's disease A peptide

Template:ABSTRACT PUBMED 23609990

Function

[IMM7_ECOLX] This protein is able to protect a cell, which harbors the plasmid ColE7 encoding colicin E7, against colicin E7, it binds specifically to the DNase-type colicin and inhibits its bactericidal activity. Dimeric ImmE7 may possess a RNase activity that cleaves its own mRNA at a specific site and thus autoregulates translational expression of the downstream ceiE7 gene as well as degradation of the upstream ceaE7 mRNA.

About this Structure

4f37 is a 6 chain structure with sequence from Escherichia coli and Mus musculus. Full crystallographic information is available from OCA.

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