This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3sem
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
| - | [[Image:3sem.png|left|200px]] | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3sem", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3sem| PDB=3sem | SCENE= }} | {{STRUCTURE_3sem| PDB=3sem | SCENE= }} | ||
| - | |||
===SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR=== | ===SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR=== | ||
| + | {{ABSTRACT_PUBMED_9851931}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/SEM5_CAEEL SEM5_CAEEL]] Acts both in vulval induction and sex myoblast migration. Presumably interacts with the kinase receptor let-23 and with a target that modifies the Ras-like protein let-60. | |
| - | + | ||
| - | + | ||
| - | -- | + | |
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3sem]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SEM OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:009851931</ref><references group="xtra"/><references/> |
[[Category: Caenorhabditis elegans]] | [[Category: Caenorhabditis elegans]] | ||
[[Category: Cohen, F E.]] | [[Category: Cohen, F E.]] | ||
| Line 36: | Line 23: | ||
[[Category: Sh3 domain]] | [[Category: Sh3 domain]] | ||
[[Category: Signal transduction]] | [[Category: Signal transduction]] | ||
| - | + | [[Category: Signaling protein-inhibitor complex]] | |
| - | + | ||
Revision as of 07:42, 16 May 2013
Contents |
SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR
Template:ABSTRACT PUBMED 9851931
Function
[SEM5_CAEEL] Acts both in vulval induction and sex myoblast migration. Presumably interacts with the kinase receptor let-23 and with a target that modifies the Ras-like protein let-60.
About this Structure
3sem is a 4 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.
Reference
- Nguyen JT, Turck CW, Cohen FE, Zuckermann RN, Lim WA. Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science. 1998 Dec 11;282(5396):2088-92. PMID:9851931
