3sem

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[[Image:3sem.png|left|200px]]
 
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{{STRUCTURE_3sem| PDB=3sem | SCENE= }}
{{STRUCTURE_3sem| PDB=3sem | SCENE= }}
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===SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR===
===SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR===
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{{ABSTRACT_PUBMED_9851931}}
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==Function==
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[[http://www.uniprot.org/uniprot/SEM5_CAEEL SEM5_CAEEL]] Acts both in vulval induction and sex myoblast migration. Presumably interacts with the kinase receptor let-23 and with a target that modifies the Ras-like protein let-60.
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{{ABSTRACT_PUBMED_9851931}}
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==About this Structure==
==About this Structure==
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3SEM is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SEM OCA].
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[[3sem]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SEM OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:9851931</ref><references group="xtra"/>
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<ref group="xtra">PMID:009851931</ref><references group="xtra"/><references/>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Cohen, F E.]]
[[Category: Cohen, F E.]]
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[[Category: Sh3 domain]]
[[Category: Sh3 domain]]
[[Category: Signal transduction]]
[[Category: Signal transduction]]
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[[Category: Signaling protein-inhibitor complex]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:47:56 2009''
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Revision as of 07:42, 16 May 2013

Template:STRUCTURE 3sem

Contents

SEM5 SH3 DOMAIN COMPLEXED WITH PEPTOID INHIBITOR

Template:ABSTRACT PUBMED 9851931

Function

[SEM5_CAEEL] Acts both in vulval induction and sex myoblast migration. Presumably interacts with the kinase receptor let-23 and with a target that modifies the Ras-like protein let-60.

About this Structure

3sem is a 4 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

  • Nguyen JT, Turck CW, Cohen FE, Zuckermann RN, Lim WA. Exploiting the basis of proline recognition by SH3 and WW domains: design of N-substituted inhibitors. Science. 1998 Dec 11;282(5396):2088-92. PMID:9851931

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