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3r3w

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[[Image:3r3w.png|left|200px]]
 
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{{STRUCTURE_3r3w| PDB=3r3w | SCENE= }}
{{STRUCTURE_3r3w| PDB=3r3w | SCENE= }}
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===Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Chloroacetate===
===Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Chloroacetate===
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{{ABSTRACT_PUBMED_21510690}}
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==Function==
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[[http://www.uniprot.org/uniprot/DEHA_RHOPA DEHA_RHOPA]] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has lower activity towards bromoacetate and chloroacetate.<ref>PMID:21510690</ref> <ref>PMID:21510690</ref>
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(as it appears on PubMed at http://www.pubmed.gov), where 21510690 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21510690}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:021510690</ref><references group="xtra"/>
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<ref group="xtra">PMID:021510690</ref><references group="xtra"/><references/>
[[Category: Haloacetate dehalogenase]]
[[Category: Haloacetate dehalogenase]]
[[Category: Rhodopseudomonas palustris]]
[[Category: Rhodopseudomonas palustris]]
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[[Category: Pai, E F.]]
[[Category: Pai, E F.]]
[[Category: Yakunin, A F.]]
[[Category: Yakunin, A F.]]
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[[Category: Alpha/beta hydrolase]]
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[[Category: Defluorinase]]
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[[Category: Facd]]
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[[Category: Hydrolase]]

Revision as of 07:50, 16 May 2013

Template:STRUCTURE 3r3w

Contents

Crystal Structure of the Fluoroacetate Dehalogenase RPA1163 - Asp110Asn/Chloroacetate

Template:ABSTRACT PUBMED 21510690

Function

[DEHA_RHOPA] Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has lower activity towards bromoacetate and chloroacetate.[1] [2]

About this Structure

3r3w is a 2 chain structure with sequence from Rhodopseudomonas palustris. Full crystallographic information is available from OCA.

Reference

  • Chan PW, Yakunin AF, Edwards EA, Pai EF. Mapping the Reaction Coordinates of Enzymatic Defluorination. J Am Chem Soc. 2011 Apr 21. PMID:21510690 doi:10.1021/ja200277d
  1. ↑ Chan PW, Yakunin AF, Edwards EA, Pai EF. Mapping the Reaction Coordinates of Enzymatic Defluorination. J Am Chem Soc. 2011 Apr 21. PMID:21510690 doi:10.1021/ja200277d
  2. ↑ Chan PW, Yakunin AF, Edwards EA, Pai EF. Mapping the Reaction Coordinates of Enzymatic Defluorination. J Am Chem Soc. 2011 Apr 21. PMID:21510690 doi:10.1021/ja200277d

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