2kzh

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[[Image:2kzh.png|left|200px]]
 
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{{STRUCTURE_2kzh| PDB=2kzh | SCENE= }}
{{STRUCTURE_2kzh| PDB=2kzh | SCENE= }}
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===Three-dimensional structure of a truncated phosphoribosylanthranilate isomerase (residues 255-384) from Escherichia coli===
===Three-dimensional structure of a truncated phosphoribosylanthranilate isomerase (residues 255-384) from Escherichia coli===
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{{ABSTRACT_PUBMED_21354426}}
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==Function==
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[[http://www.uniprot.org/uniprot/TRPC_ECOLI TRPC_ECOLI]] Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.
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{{ABSTRACT_PUBMED_21354426}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:021354426</ref><ref group="xtra">PMID:016008567</ref><references group="xtra"/>
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<ref group="xtra">PMID:021354426</ref><ref group="xtra">PMID:016008567</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Phosphoribosylanthranilate isomerase]]
[[Category: Phosphoribosylanthranilate isomerase]]

Revision as of 07:53, 16 May 2013

Template:STRUCTURE 2kzh

Contents

Three-dimensional structure of a truncated phosphoribosylanthranilate isomerase (residues 255-384) from Escherichia coli

Template:ABSTRACT PUBMED 21354426

Function

[TRPC_ECOLI] Bifunctional enzyme that catalyzes two sequential steps of tryptophan biosynthetic pathway. The first reaction is catalyzed by the isomerase, coded by the TrpF domain; the second reaction is catalyzed by the synthase, coded by the TrpC domain.

About this Structure

2kzh is a 1 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

  • Setiyaputra S, Mackay JP, Patrick WM. The structure of a truncated phosphoribosylanthranilate isomerase suggests a unified model for evolution of the (betaalpha)8 barrel fold. J Mol Biol. 2011 Apr 29;408(2):291-303. Epub 2011 Feb 25. PMID:21354426 doi:10.1016/j.jmb.2011.02.048
  • Patrick WM, Blackburn JM. In vitro selection and characterization of a stable subdomain of phosphoribosylanthranilate isomerase. FEBS J. 2005 Jul;272(14):3684-97. PMID:16008567 doi:10.1111/j.1742-4658.2005.04794.x

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OCA

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