3tgf

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[[Image:3tgf.png|left|200px]]
 
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{{STRUCTURE_3tgf| PDB=3tgf | SCENE= }}
{{STRUCTURE_3tgf| PDB=3tgf | SCENE= }}
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===THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA===
===THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA===
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{{ABSTRACT_PUBMED_2050136}}
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==Function==
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[[http://www.uniprot.org/uniprot/TGFA_HUMAN TGFA_HUMAN]] TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.
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{{ABSTRACT_PUBMED_2050136}}
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==About this Structure==
==About this Structure==
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3TGF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TGF OCA].
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[[3tgf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TGF OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:2050136</ref><references group="xtra"/>
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<ref group="xtra">PMID:002050136</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Campbell, I D.]]
[[Category: Campbell, I D.]]
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[[Category: Wilkinson, A J.]]
[[Category: Wilkinson, A J.]]
[[Category: Growth factor]]
[[Category: Growth factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:31:38 2009''
 

Revision as of 07:58, 16 May 2013

Template:STRUCTURE 3tgf

Contents

THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA

Template:ABSTRACT PUBMED 2050136

Function

[TGFA_HUMAN] TGF alpha is a mitogenic polypeptide that is able to bind to the EGF receptor/EGFR and to act synergistically with TGF beta to promote anchorage-independent cell proliferation in soft agar.

About this Structure

3tgf is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

  • Harvey TS, Wilkinson AJ, Tappin MJ, Cooke RM, Campbell ID. The solution structure of human transforming growth factor alpha. Eur J Biochem. 1991 Jun 15;198(3):555-62. PMID:2050136

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