3tmk

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[[Image:3tmk.png|left|200px]]
 
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{{STRUCTURE_3tmk| PDB=3tmk | SCENE= }}
{{STRUCTURE_3tmk| PDB=3tmk | SCENE= }}
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===CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION===
===CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION===
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{{ABSTRACT_PUBMED_9521686}}
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==Function==
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[[http://www.uniprot.org/uniprot/KTHY_YEAST KTHY_YEAST]] Catalyzes the conversion of dTMP to dTDP.
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==About this Structure==
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[[3tmk]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TMK OCA].
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(as it appears on PubMed at http://www.pubmed.gov), where 9521686 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9521686}}
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==About this Structure==
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==See Also==
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3TMK is a 8 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TMK OCA].
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*[[Thymidylate kinase|Thymidylate kinase]]
==Reference==
==Reference==
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<ref group="xtra">PMID:9521686</ref><references group="xtra"/>
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<ref group="xtra">PMID:009521686</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: DTMP kinase]]
[[Category: DTMP kinase]]
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[[Category: Kinase]]
[[Category: Kinase]]
[[Category: Phosphotransferase]]
[[Category: Phosphotransferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 12:13:00 2009''
 

Revision as of 08:05, 16 May 2013

Template:STRUCTURE 3tmk

Contents

CRYSTAL STRUCTURE OF YEAST THYMIDYLATE KINASE COMPLEXED WITH THE BISUBSTRATE INHIBITOR TP5A AT 2.0 A RESOLUTION: IMPLICATIONS FOR CATALYSIS AND AZT ACTIVATION

Template:ABSTRACT PUBMED 9521686

Function

[KTHY_YEAST] Catalyzes the conversion of dTMP to dTDP.

About this Structure

3tmk is a 8 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

See Also

Reference

  • Lavie A, Konrad M, Brundiers R, Goody RS, Schlichting I, Reinstein J. Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation. Biochemistry. 1998 Mar 17;37(11):3677-86. PMID:9521686 doi:10.1021/bi9720787

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OCA

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