2lsg
From Proteopedia
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{{STRUCTURE_2lsg| PDB=2lsg | SCENE= }} | {{STRUCTURE_2lsg| PDB=2lsg | SCENE= }} | ||
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===Solution structure of the mouse Rev1 C-terminal domain=== | ===Solution structure of the mouse Rev1 C-terminal domain=== | ||
| + | {{ABSTRACT_PUBMED_22700975}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/REV1_MOUSE REV1_MOUSE]] Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.<ref>PMID:11711549</ref> | ||
==About this Structure== | ==About this Structure== | ||
[[2lsg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSG OCA]. | [[2lsg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LSG OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022700975</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Liu, J.]] | [[Category: Liu, J.]] | ||
Revision as of 07:38, 19 June 2013
Contents |
Solution structure of the mouse Rev1 C-terminal domain
Template:ABSTRACT PUBMED 22700975
Function
[REV1_MOUSE] Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents.[1]
About this Structure
2lsg is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.
Reference
- Wojtaszek J, Liu J, D'Souza S, Wang S, Xue Y, Walker GC, Zhou P. Multifaceted recognition of vertebrate Rev1 by translesion polymerases zeta and kappa. J Biol Chem. 2012 Jul 27;287(31):26400-8. doi: 10.1074/jbc.M112.380998. Epub 2012, Jun 14. PMID:22700975 doi:10.1074/jbc.M112.380998
- ↑ Masuda Y, Takahashi M, Fukuda S, Sumii M, Kamiya K. Mechanisms of dCMP transferase reactions catalyzed by mouse Rev1 protein. J Biol Chem. 2002 Jan 25;277(4):3040-6. Epub 2001 Nov 15. PMID:11711549 doi:10.1074/jbc.M110149200
