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2ql5

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[[Image:2ql5.png|left|200px]]
 
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{{STRUCTURE_2ql5| PDB=2ql5 | SCENE= }}
{{STRUCTURE_2ql5| PDB=2ql5 | SCENE= }}
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===Crystal Structure of caspase-7 with inhibitor AC-DMQD-CHO===
===Crystal Structure of caspase-7 with inhibitor AC-DMQD-CHO===
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{{ABSTRACT_PUBMED_17697120}}
{{ABSTRACT_PUBMED_17697120}}
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==Function==
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[[http://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN]] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
==About this Structure==
==About this Structure==
[[2ql5]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QL5 OCA].
[[2ql5]] is a 7 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QL5 OCA].
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==See Also==
 
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*[[Caspase|Caspase]]
 
==Reference==
==Reference==
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<ref group="xtra">PMID:017697120</ref><references group="xtra"/>
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<ref group="xtra">PMID:017697120</ref><references group="xtra"/><references/>
[[Category: Caspase-7]]
[[Category: Caspase-7]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]

Revision as of 07:49, 19 June 2013

Template:STRUCTURE 2ql5

Contents

Crystal Structure of caspase-7 with inhibitor AC-DMQD-CHO

Template:ABSTRACT PUBMED 17697120

Function

[CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

About this Structure

2ql5 is a 7 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Proteopedia Page Contributors and Editors (what is this?)

OCA

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