2xdi
From Proteopedia
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{{STRUCTURE_2xdi| PDB=2xdi | SCENE= }} | {{STRUCTURE_2xdi| PDB=2xdi | SCENE= }} | ||
| + | ===Tryptophan repressor with L75F mutation in its apo form (no L- tryptophan bound)=== | ||
| + | {{ABSTRACT_PUBMED_12356295}} | ||
| - | === | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/TRPR_ECO57 TRPR_ECO57]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity). | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:012356295</ref><references group="xtra"/> | + | <ref group="xtra">PMID:012356295</ref><references group="xtra"/><references/> |
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Copie, V.]] | [[Category: Copie, V.]] | ||
Revision as of 08:07, 19 June 2013
Contents |
Tryptophan repressor with L75F mutation in its apo form (no L- tryptophan bound)
Template:ABSTRACT PUBMED 12356295
Function
[TRPR_ECO57] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity).
About this Structure
2xdi is a 2 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA.
Reference
- Tyler R, Pelczer I, Carey J, Copie V. Three-dimensional solution NMR structure of Apo-L75F-TrpR, a temperature-sensitive mutant of the tryptophan repressor protein. Biochemistry. 2002 Oct 8;41(40):11954-62. PMID:12356295
