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2xdi

From Proteopedia

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[[Image:2xdi.png|left|200px]]
 
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{{STRUCTURE_2xdi| PDB=2xdi | SCENE= }}
{{STRUCTURE_2xdi| PDB=2xdi | SCENE= }}
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===Tryptophan repressor with L75F mutation in its apo form (no L- tryptophan bound)===
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{{ABSTRACT_PUBMED_12356295}}
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===TRYPTOPHAN REPRESSOR WITH L75F MUTATION IN ITS APO FORM (NO L-TRYPTOPHAN BOUND)===
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==Function==
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[[http://www.uniprot.org/uniprot/TRPR_ECO57 TRPR_ECO57]] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity).
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{{ABSTRACT_PUBMED_12356295}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:012356295</ref><references group="xtra"/>
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<ref group="xtra">PMID:012356295</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Copie, V.]]
[[Category: Copie, V.]]

Revision as of 08:07, 19 June 2013

Template:STRUCTURE 2xdi

Contents

Tryptophan repressor with L75F mutation in its apo form (no L- tryptophan bound)

Template:ABSTRACT PUBMED 12356295

Function

[TRPR_ECO57] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity).

About this Structure

2xdi is a 2 chain structure with sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

  • Tyler R, Pelczer I, Carey J, Copie V. Three-dimensional solution NMR structure of Apo-L75F-TrpR, a temperature-sensitive mutant of the tryptophan repressor protein. Biochemistry. 2002 Oct 8;41(40):11954-62. PMID:12356295

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OCA

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