3q0n
From Proteopedia
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{{STRUCTURE_3q0n| PDB=3q0n | SCENE= }} | {{STRUCTURE_3q0n| PDB=3q0n | SCENE= }} | ||
===Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with erk2 NRE=== | ===Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with erk2 NRE=== | ||
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==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[3q0n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0N OCA]. | [[3q0n]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q0N OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021397187</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Hall, T M.T.]] | [[Category: Hall, T M.T.]] | ||
Revision as of 08:52, 19 June 2013
Contents |
Crystal structure of the PUMILIO-homology domain from Human PUMILIO1 in complex with erk2 NRE
Template:ABSTRACT PUBMED 21397187
Function
[PUM1_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. May be required to support proliferation and self-renewal of stem cells (By similarity).
About this Structure
3q0n is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Lu G, Hall TM. Alternate modes of cognate RNA recognition by human PUMILIO proteins. Structure. 2011 Mar 9;19(3):361-7. PMID:21397187 doi:10.1016/j.str.2010.12.019
