1hbj
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:1hbj.png|left|200px]] | ||
| - | |||
{{STRUCTURE_1hbj| PDB=1hbj | SCENE= }} | {{STRUCTURE_1hbj| PDB=1hbj | SCENE= }} | ||
| + | ===X-ray Crystal structure of complex between Torpedo californica AChE and a reversible inhibitor, 4-Amino-5-fluoro-2-methyl-3-(3-trifluoroacetylbenzylthiomethyl)quinoline=== | ||
| + | {{ABSTRACT_PUBMED_11563919}} | ||
| - | == | + | ==Function== |
| - | + | [[http://www.uniprot.org/uniprot/ACES_TORCA ACES_TORCA]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions. | |
| - | + | ||
==About this Structure== | ==About this Structure== | ||
[[1hbj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HBJ OCA]. | [[1hbj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Torpedo_californica Torpedo californica]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HBJ OCA]. | ||
| - | |||
| - | ==See Also== | ||
| - | *[[Acetylcholinesterase|Acetylcholinesterase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:011563919</ref><references group="xtra"/> | + | <ref group="xtra">PMID:011563919</ref><references group="xtra"/><references/> |
[[Category: Acetylcholinesterase]] | [[Category: Acetylcholinesterase]] | ||
[[Category: Torpedo californica]] | [[Category: Torpedo californica]] | ||
| - | [[Category: Doucet | + | [[Category: Doucet, C.]] |
[[Category: Greenblatt, H M.]] | [[Category: Greenblatt, H M.]] | ||
[[Category: Kryger, G.]] | [[Category: Kryger, G.]] | ||
Revision as of 10:22, 19 June 2013
Contents |
X-ray Crystal structure of complex between Torpedo californica AChE and a reversible inhibitor, 4-Amino-5-fluoro-2-methyl-3-(3-trifluoroacetylbenzylthiomethyl)quinoline
Template:ABSTRACT PUBMED 11563919
Function
[ACES_TORCA] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. May be involved in cell-cell interactions.
About this Structure
1hbj is a 1 chain structure with sequence from Torpedo californica. Full crystallographic information is available from OCA.
Reference
- Doucet-Personeni C, Bentley PD, Fletcher RJ, Kinkaid A, Kryger G, Pirard B, Taylor A, Taylor R, Taylor J, Viner R, Silman I, Sussman JL, Greenblatt HM, Lewis T. A structure-based design approach to the development of novel, reversible AChE inhibitors. J Med Chem. 2001 Sep 27;44(20):3203-15. PMID:11563919
