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4dqw
From Proteopedia
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| - | [[Image:4dqw.jpg|left|200px]] | ||
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{{STRUCTURE_4dqw| PDB=4dqw | SCENE= }} | {{STRUCTURE_4dqw| PDB=4dqw | SCENE= }} | ||
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===Crystal Structure Analysis of PA3770=== | ===Crystal Structure Analysis of PA3770=== | ||
| + | {{ABSTRACT_PUBMED_23643948}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/Q9HXM5_PSEAE Q9HXM5_PSEAE]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964] | ||
==About this Structure== | ==About this Structure== | ||
[[4dqw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DQW OCA]. | [[4dqw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DQW OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023643948</ref><references group="xtra"/><references/> | ||
[[Category: IMP dehydrogenase]] | [[Category: IMP dehydrogenase]] | ||
[[Category: Pseudomonas aeruginosa pao1]] | [[Category: Pseudomonas aeruginosa pao1]] | ||
Revision as of 13:27, 19 June 2013
Contents |
Crystal Structure Analysis of PA3770
Template:ABSTRACT PUBMED 23643948
Function
[Q9HXM5_PSEAE] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity).[HAMAP-Rule:MF_01964]
About this Structure
4dqw is a 2 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.
Reference
- Labesse G, Alexandre T, Vaupre L, Salard-Arnaud I, Him JL, Raynal B, Bron P, Munier-Lehmann H. MgATP Regulates Allostery and Fiber Formation in IMPDHs. Structure. 2013 Jun 4;21(6):975-85. doi: 10.1016/j.str.2013.03.011. Epub 2013 May, 2. PMID:23643948 doi:10.1016/j.str.2013.03.011
