3rz2
From Proteopedia
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{{STRUCTURE_3rz2| PDB=3rz2 | SCENE= }} | {{STRUCTURE_3rz2| PDB=3rz2 | SCENE= }} | ||
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===Crystal of Prl-1 complexed with peptide=== | ===Crystal of Prl-1 complexed with peptide=== | ||
| + | {{ABSTRACT_PUBMED_22009749}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/TP4A1_RAT TP4A1_RAT]] Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[3rz2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZ2 OCA]. | [[3rz2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RZ2 OCA]. | ||
| - | == | + | ==Reference== |
| - | + | <ref group="xtra">PMID:022009749</ref><references group="xtra"/><references/> | |
[[Category: Protein-tyrosine-phosphatase]] | [[Category: Protein-tyrosine-phosphatase]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
Revision as of 13:37, 19 June 2013
Contents |
Crystal of Prl-1 complexed with peptide
Template:ABSTRACT PUBMED 22009749
Function
[TP4A1_RAT] Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues (By similarity).
About this Structure
3rz2 is a 4 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Bai Y, Luo Y, Liu S, Zhang L, Shen K, Dong Y, Walls CD, Quilliam LA, Wells CD, Cao Y, Zhang ZY. PRL-1 protein promotes ERK1/2 and RhoA protein activation through a non-canonical interaction with the Src homology 3 domain of p115 Rho GTPase-activating protein. J Biol Chem. 2011 Dec 9;286(49):42316-24. Epub 2011 Oct 18. PMID:22009749 doi:10.1074/jbc.M111.286302
