4dkk

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'''Unreleased structure'''
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{{STRUCTURE_4dkk| PDB=4dkk | SCENE= }}
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===The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer===
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{{ABSTRACT_PUBMED_23524536}}
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The entry 4dkk is ON HOLD until Mar 20 2014
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==Function==
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[[http://www.uniprot.org/uniprot/STAU1_HUMAN STAU1_HUMAN]] Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.
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Authors: Gleghorn, M.L.
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==About this Structure==
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[[4dkk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DKK OCA].
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Description: The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer
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==Reference==
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<ref group="xtra">PMID:023524536</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Gleghorn, M L.]]
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[[Category: Beta sheet]]
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[[Category: Dimerization]]
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[[Category: Protein binding]]
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[[Category: Rbd]]
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[[Category: Rna binding protein]]
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[[Category: Swapping-motif]]

Revision as of 15:05, 19 June 2013

Template:STRUCTURE 4dkk

Contents

The X-ray Crystal Structure of the Human STAU1 SSM-'RBD'5 Domain-Swapped Dimer

Template:ABSTRACT PUBMED 23524536

Function

[STAU1_HUMAN] Binds double-stranded RNA (regardless of the sequence) and tubulin. May play a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.

About this Structure

4dkk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Gleghorn ML, Gong C, Kielkopf CL, Maquat LE. Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay. Nat Struct Mol Biol. 2013 Apr;20(4):515-24. doi: 10.1038/nsmb.2528. Epub 2013 Mar, 24. PMID:23524536 doi:10.1038/nsmb.2528

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OCA

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