4khr
From Proteopedia
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| - | + | {{STRUCTURE_4khr| PDB=4khr | SCENE= }} | |
| + | ===HCV NS5B GT1A C316Y with GSK5852=== | ||
| + | {{ABSTRACT_PUBMED_23672667}} | ||
| - | + | ==About this Structure== | |
| + | [[4khr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHR OCA]. | ||
| - | + | ==Reference== | |
| - | + | <ref group="xtra">PMID:023672667</ref><references group="xtra"/><references/> | |
| - | + | [[Category: Hepatitis c virus subtype 1a]] | |
| + | [[Category: RNA-directed RNA polymerase]] | ||
| + | [[Category: Kahler, K M.]] | ||
| + | [[Category: Shotwell, J B.]] | ||
| + | [[Category: Williams, S P.]] | ||
| + | [[Category: Boron]] | ||
| + | [[Category: Hcv ns5b]] | ||
| + | [[Category: Hcv polymerase]] | ||
| + | [[Category: P66]] | ||
| + | [[Category: P70]] | ||
| + | [[Category: Polymerase]] | ||
| + | [[Category: Replication-replication inhibitor complex]] | ||
| + | [[Category: Rna dependent rna polymerase]] | ||
| + | [[Category: Rna directed rna polymerase]] | ||
| + | [[Category: Rns dependent rna polymerase]] | ||
| + | [[Category: Site iv inhibitor]] | ||
Revision as of 15:09, 19 June 2013
HCV NS5B GT1A C316Y with GSK5852
Template:ABSTRACT PUBMED 23672667
About this Structure
4khr is a 2 chain structure with sequence from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.
Reference
- Maynard A, Crosby RM, Ellis B, Hamatake R, Hong Z, Johns BA, Kahler KM, Koble C, Leivers AL, Leivers MR, Mathis A, Peat AJ, Pouliot JJ, Roberts CD, Samano V, Schmidt RM, Smith GK, Spaltenstein A, Stewart EL, Thommes P, Turner EM, Voitenleitner C, Walker JT, Waitt G, Weatherhead J, Weaver KL, Williams S, Wright L, Xiong ZZ, Haigh D, Shotwell JB. Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. J Med Chem. 2013 May 14. PMID:23672667 doi:10.1021/jm400317w
Categories: Hepatitis c virus subtype 1a | RNA-directed RNA polymerase | Kahler, K M. | Shotwell, J B. | Williams, S P. | Boron | Hcv ns5b | Hcv polymerase | P66 | P70 | Polymerase | Replication-replication inhibitor complex | Rna dependent rna polymerase | Rna directed rna polymerase | Rns dependent rna polymerase | Site iv inhibitor
