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4gcl

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'''Unreleased structure'''
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{{STRUCTURE_4gcl| PDB=4gcl | SCENE= }}
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===structure of no-dna factor===
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{{ABSTRACT_PUBMED_23754405}}
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The entry 4gcl is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/Q1R4V1_ECOUT Q1R4V1_ECOUT]] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity).[HAMAP-Rule:MF_01839][SAAS:SAAS011075_004_088010]
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Authors: Schumacher, M.A.
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==About this Structure==
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[[4gcl]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_uti89 Escherichia coli uti89]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GCL OCA].
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Description: structure of no-dna factor
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==Reference==
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<ref group="xtra">PMID:023754405</ref><references group="xtra"/><references/>
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[[Category: Escherichia coli uti89]]
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[[Category: Schumacher, M A.]]
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[[Category: Dna binding protein]]
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[[Category: Dna binding protein-dna complex]]

Revision as of 15:10, 19 June 2013

Template:STRUCTURE 4gcl

Contents

structure of no-dna factor

Template:ABSTRACT PUBMED 23754405

Function

[Q1R4V1_ECOUT] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity).[HAMAP-Rule:MF_01839][SAAS:SAAS011075_004_088010]

About this Structure

4gcl is a 12 chain structure with sequence from Escherichia coli uti89. Full crystallographic information is available from OCA.

Reference

  • Tonthat NK, Milam SL, Chinnam N, Whitfill T, Margolin W, Schumacher MA. SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid. Proc Natl Acad Sci U S A. 2013 Jun 10. PMID:23754405 doi:10.1073/pnas.1221036110

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OCA

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