4hj0

(Difference between revisions)

Revision as of 15:28, 19 June 2013

[GIPR_HUMAN] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

4hj0 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Ravn P, Madhurantakam C, Kunze S, Matthews E, Priest C, O'brien S, Collinson A, Papworth M, Fritsch-Fredin M, Jermutus L, Benthem L, Gruetter M, Jackson RH. Structural and Pharmacological Characterisation of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-Dependent Insulinotropic Polypeptide Receptor. J Biol Chem. 2013 May 20. PMID:23689510 doi:10.1074/jbc.M112.426288

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-'''Unreleased structure'''
+{{STRUCTURE_4hj0|  PDB=4hj0  |  SCENE=  }}
+===Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution===
+{{ABSTRACT_PUBMED_23689510}}
-The entry 4hj0 is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/GIPR_HUMAN GIPR_HUMAN]] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
-Authors: Madhurantakam, C., Ravn, P., Gruetter, M.G., Jackson, R.H.
+==About this Structure==
+[[4hj0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ0 OCA].
-Description: Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution
+==Reference==
+<ref group="xtra">PMID:023689510</ref><references group="xtra"/><references/>
+[[Category: Homo sapiens]]
+[[Category: Gruetter, M G.]]
+[[Category: Jackson, R H.]]
+[[Category: Madhurantakam, C.]]
+[[Category: Ravn, P.]]
+[[Category: Glucagon receptor sub-family recognition fold]]
+[[Category: Immune system]]