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4hj0

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'''Unreleased structure'''
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{{STRUCTURE_4hj0| PDB=4hj0 | SCENE= }}
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===Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution===
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{{ABSTRACT_PUBMED_23689510}}
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The entry 4hj0 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/GIPR_HUMAN GIPR_HUMAN]] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
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Authors: Madhurantakam, C., Ravn, P., Gruetter, M.G., Jackson, R.H.
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==About this Structure==
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[[4hj0]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJ0 OCA].
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Description: Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution
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==Reference==
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<ref group="xtra">PMID:023689510</ref><references group="xtra"/><references/>
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[[Category: Homo sapiens]]
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[[Category: Gruetter, M G.]]
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[[Category: Jackson, R H.]]
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[[Category: Madhurantakam, C.]]
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[[Category: Ravn, P.]]
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[[Category: Glucagon receptor sub-family recognition fold]]
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[[Category: Immune system]]

Revision as of 15:28, 19 June 2013

Template:STRUCTURE 4hj0

Contents

Crystal structure of the human GIPr ECD in complex with Gipg013 Fab at 3-A resolution

Template:ABSTRACT PUBMED 23689510

Function

[GIPR_HUMAN] This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.

About this Structure

4hj0 is a 6 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Ravn P, Madhurantakam C, Kunze S, Matthews E, Priest C, O'brien S, Collinson A, Papworth M, Fritsch-Fredin M, Jermutus L, Benthem L, Gruetter M, Jackson RH. Structural and Pharmacological Characterisation of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-Dependent Insulinotropic Polypeptide Receptor. J Biol Chem. 2013 May 20. PMID:23689510 doi:10.1074/jbc.M112.426288

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