3ef0
From Proteopedia
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{{STRUCTURE_3ef0| PDB=3ef0 | SCENE= }} | {{STRUCTURE_3ef0| PDB=3ef0 | SCENE= }} | ||
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===The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase=== | ===The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase=== | ||
| + | {{ABSTRACT_PUBMED_19026779}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/FCP1_SCHPO FCP1_SCHPO]] Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. | ||
==About this Structure== | ==About this Structure== | ||
[[3ef0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EF0 OCA]. | [[3ef0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EF0 OCA]. | ||
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| - | ==See Also== | ||
| - | *[[RNA polymerase|RNA polymerase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:019026779</ref><references group="xtra"/> | + | <ref group="xtra">PMID:019026779</ref><references group="xtra"/><references/> |
[[Category: Phosphoprotein phosphatase]] | [[Category: Phosphoprotein phosphatase]] | ||
[[Category: Schizosaccharomyces pombe]] | [[Category: Schizosaccharomyces pombe]] | ||
Revision as of 15:30, 19 June 2013
Contents |
The Structure of Fcp1, an essential RNA polymerase II CTD phosphatase
Template:ABSTRACT PUBMED 19026779
Function
[FCP1_SCHPO] Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II.
About this Structure
3ef0 is a 1 chain structure with sequence from Schizosaccharomyces pombe. Full crystallographic information is available from OCA.
Reference
- Ghosh A, Shuman S, Lima CD. The structure of Fcp1, an essential RNA polymerase II CTD phosphatase. Mol Cell. 2008 Nov 21;32(4):478-90. PMID:19026779 doi:10.1016/j.molcel.2008.09.021
