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1vuu

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(New page: {{Large structure}} {{STRUCTURE_1vuu| PDB=1vuu | SCENE= }} ===Atomic-level structure of the entire HIV-1 capsid (186 hexamers + 12 pentamers)=== {{ABSTRACT_PUBMED_23719463}} ==Functi...)
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Revision as of 16:01, 19 June 2013

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Template:STRUCTURE 1vuu

Contents

Atomic-level structure of the entire HIV-1 capsid (186 hexamers + 12 pentamers)

Template:ABSTRACT PUBMED 23719463

Function

[Q79791_9HIV1] Capsid protein p24 forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex (By similarity).[SAAS:SAAS000071_004_008806] Nucleocapsid protein p7 encapsulates and protects viral dimeric unspliced (genomic) RNA. Binds these RNAs through its zinc fingers (By similarity).[SAAS:SAAS000071_004_011858]

About this Structure

1vuu is a 55 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Zhao G, Perilla JR, Yufenyuy EL, Meng X, Chen B, Ning J, Ahn J, Gronenborn AM, Schulten K, Aiken C, Zhang P. Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics. Nature. 2013 May 30;497(7451):643-6. doi: 10.1038/nature12162. PMID:23719463 doi:10.1038/nature12162

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