4khm

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{{STRUCTURE_4khm| PDB=4khm | SCENE= }}
{{STRUCTURE_4khm| PDB=4khm | SCENE= }}
===HCV NS5B GT1A with GSK5852===
===HCV NS5B GT1A with GSK5852===
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{{ABSTRACT_PUBMED_23672667}}
==About this Structure==
==About this Structure==
[[4khm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHM OCA].
[[4khm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KHM OCA].
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==Reference==
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<ref group="xtra">PMID:023672667</ref><references group="xtra"/><references/>
[[Category: Hepatitis c virus subtype 1a]]
[[Category: Hepatitis c virus subtype 1a]]
[[Category: RNA-directed RNA polymerase]]
[[Category: RNA-directed RNA polymerase]]

Revision as of 16:07, 19 June 2013

Template:STRUCTURE 4khm

HCV NS5B GT1A with GSK5852

Template:ABSTRACT PUBMED 23672667

About this Structure

4khm is a 2 chain structure with sequence from Hepatitis c virus subtype 1a. Full crystallographic information is available from OCA.

Reference

  • Maynard A, Crosby RM, Ellis B, Hamatake R, Hong Z, Johns BA, Kahler KM, Koble C, Leivers AL, Leivers MR, Mathis A, Peat AJ, Pouliot JJ, Roberts CD, Samano V, Schmidt RM, Smith GK, Spaltenstein A, Stewart EL, Thommes P, Turner EM, Voitenleitner C, Walker JT, Waitt G, Weatherhead J, Weaver KL, Williams S, Wright L, Xiong ZZ, Haigh D, Shotwell JB. Discovery of a Potent Boronic Acid Derived Inhibitor of the HCV RNA-Dependent RNA Polymerase. J Med Chem. 2013 May 14. PMID:23672667 doi:10.1021/jm400317w

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