4b2w

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m (Protected "4b2w" [edit=sysop:move=sysop])
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'''Unreleased structure'''
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{{STRUCTURE_4b2w| PDB=4b2w | SCENE= }}
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===Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor===
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{{ABSTRACT_PUBMED_23138692}}
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The entry 4b2w is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/G3XCK4_PSEAI G3XCK4_PSEAI]] Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity).[RuleBase:RU003706]
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Authors: Alphey, M.S., Pirrie, L., Torrie, L., Gardiner, M., Westwood, N.J., Gray, D., Naismith, J.H.
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==About this Structure==
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[[4b2w]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_pao1 Pseudomonas aeruginosa pao1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B2W OCA].
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Description: Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor
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==Reference==
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<ref group="xtra">PMID:023138692</ref><references group="xtra"/><references/>
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[[Category: 1L-myo-inositol 1-phosphate cytidylyltransferase]]
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[[Category: Pseudomonas aeruginosa pao1]]
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[[Category: Alphey, M S.]]
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[[Category: Gardiner, M.]]
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[[Category: Gray, D.]]
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[[Category: Naismith, J H.]]
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[[Category: Pirrie, L.]]
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[[Category: Torrie, L.]]
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[[Category: Westwood, N J.]]
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[[Category: Allosteric inhibitor]]
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[[Category: Transferase]]

Revision as of 16:16, 19 June 2013

Template:STRUCTURE 4b2w

Contents

Pseudomonas aeruginosa RmlA in complex with allosteric inhibitor

Template:ABSTRACT PUBMED 23138692

Function

[G3XCK4_PSEAI] Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity).[RuleBase:RU003706]

About this Structure

4b2w is a 4 chain structure with sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.

Reference

  • Alphey MS, Pirrie L, Torrie LS, Boulkeroura WA, Gardiner M, Sarkar A, Maringer M, Oehlmann W, Brenk R, Scherman MS, McNeil M, Rejzek M, Field RA, Singh M, Gray D, Westwood NJ, Naismith JH. Allosteric Competitive Inhibitors of the Glucose-1-Phosphate Thymidylyltransferase (RmlA) from Pseudomonas aeruginosa. ACS Chem Biol. 2012 Nov 8. PMID:23138692 doi:10.1021/cb300426u

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OCA

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