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2wgm

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[[Image:2wgm.png|left|200px]]
 
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{{STRUCTURE_2wgm| PDB=2wgm | SCENE= }}
{{STRUCTURE_2wgm| PDB=2wgm | SCENE= }}
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===Complete ion-coordination structure in the rotor ring of Na-dependent F-ATP synthase===
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{{ABSTRACT_PUBMED_19500592}}
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===COMPLETE ION-COORDINATION STRUCTURE IN THE ROTOR RING OF NA-DEPENDENT F-ATP SYNTHASE===
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==Function==
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[[http://www.uniprot.org/uniprot/ATPL_ILYTA ATPL_ILYTA]] F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane sodium channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to sodium translocation.[HAMAP-Rule:MF_01396] Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of 11 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.[HAMAP-Rule:MF_01396]
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{{ABSTRACT_PUBMED_19500592}}
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==About this Structure==
==About this Structure==
[[2wgm]] is a 44 chain structure with sequence from [http://en.wikipedia.org/wiki/Ilyobacter_tartaricus Ilyobacter tartaricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WGM OCA].
[[2wgm]] is a 44 chain structure with sequence from [http://en.wikipedia.org/wiki/Ilyobacter_tartaricus Ilyobacter tartaricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WGM OCA].
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==See Also==
 
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*[[ATP synthase|ATP synthase]]
 
==Reference==
==Reference==
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<ref group="xtra">PMID:019500592</ref><references group="xtra"/>
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<ref group="xtra">PMID:019500592</ref><references group="xtra"/><references/>
[[Category: Ilyobacter tartaricus]]
[[Category: Ilyobacter tartaricus]]
[[Category: Diederichs, K.]]
[[Category: Diederichs, K.]]
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[[Category: Atp synthesis]]
[[Category: Atp synthesis]]
[[Category: C-ring structure]]
[[Category: C-ring structure]]
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[[Category: Cell inner membrane]]
 
[[Category: Cell membrane]]
[[Category: Cell membrane]]
[[Category: F1fo-atp synthase rotor]]
[[Category: F1fo-atp synthase rotor]]
[[Category: Hydrogen ion transport]]
[[Category: Hydrogen ion transport]]
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[[Category: Ilyobacter tartaricus]]
 
[[Category: Ion coordination and selectivity]]
[[Category: Ion coordination and selectivity]]
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[[Category: Ion transport]]
 
[[Category: Lipid-binding]]
[[Category: Lipid-binding]]
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[[Category: Membrane]]
 
[[Category: Membrane protein]]
[[Category: Membrane protein]]
[[Category: Sodium transport]]
[[Category: Sodium transport]]

Revision as of 16:25, 19 June 2013

Template:STRUCTURE 2wgm

Contents

Complete ion-coordination structure in the rotor ring of Na-dependent F-ATP synthase

Template:ABSTRACT PUBMED 19500592

Function

[ATPL_ILYTA] F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane sodium channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to sodium translocation.[HAMAP-Rule:MF_01396] Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of 11 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.[HAMAP-Rule:MF_01396]

About this Structure

2wgm is a 44 chain structure with sequence from Ilyobacter tartaricus. Full crystallographic information is available from OCA.

Reference

  • Meier T, Krah A, Bond PJ, Pogoryelov D, Diederichs K, Faraldo-Gomez JD. Complete ion-coordination structure in the rotor ring of Na+-dependent F-ATP synthases. J Mol Biol. 2009 Aug 14;391(2):498-507. Epub 2009 Jun 3. PMID:19500592 doi:10.1016/j.jmb.2009.05.082

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