4gh8

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'''Unreleased structure'''
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{{STRUCTURE_4gh8| PDB=4gh8 | SCENE= }}
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===Crystal structure of a 'humanized' E. coli dihydrofolate reductase===
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The entry 4gh8 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
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Authors: French, J.B., Liu, C.T., Hanoian, P., Pringle, T.H., Hammes-Schiffer, S., Benkovic, S.J.
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==About this Structure==
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[[4gh8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GH8 OCA].
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Description: Crystal structure of a 'humanized' E. coli dihydrofolate reductase
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[[Category: Dihydrofolate reductase]]
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[[Category: Escherichia coli k-12]]
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[[Category: Benkovic, S J.]]
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[[Category: French, J B.]]
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[[Category: Hammes-Schiffer, S.]]
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[[Category: Hanoian, P.]]
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[[Category: Liu, C T.]]
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[[Category: Pringle, T H.]]
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[[Category: Dihydrofolate reductase]]
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[[Category: Enzyme catalysis]]
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[[Category: Evolution]]
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[[Category: Oxidoreductase]]
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[[Category: Tetrahydrofolate]]

Revision as of 18:13, 19 June 2013

Template:STRUCTURE 4gh8

Crystal structure of a 'humanized' E. coli dihydrofolate reductase

Function

[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

About this Structure

4gh8 is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

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OCA

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