4h85
From Proteopedia
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- | + | {{STRUCTURE_4h85| PDB=4h85 | SCENE= }} | |
+ | ===Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(R)-alpha-chloroisocaproate complex with ADP=== | ||
- | + | ==Function== | |
+ | [[http://www.uniprot.org/uniprot/BCKD_RAT BCKD_RAT]] Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex. | ||
- | + | ==About this Structure== | |
- | + | [[4h85]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4H85 OCA]. | |
- | + | [[Category: Rattus norvegicus]] | |
+ | [[Category: Chuang, D T.]] | ||
+ | [[Category: Chuang, J L.]] | ||
+ | [[Category: Gui, W J.]] | ||
+ | [[Category: Li, J.]] | ||
+ | [[Category: Tso, S C.]] | ||
+ | [[Category: Wynn, R M.]] | ||
+ | [[Category: Allosteric kinase inhibitor]] | ||
+ | [[Category: Bergerat nucleotide-binding fold]] | ||
+ | [[Category: Branched-chain alpha-ketoacid]] | ||
+ | [[Category: Branched-chain amino acid]] | ||
+ | [[Category: Diabetes and obesity]] | ||
+ | [[Category: Ghkl protein kinase]] | ||
+ | [[Category: Maple syrup urine disease]] | ||
+ | [[Category: Protein kinase]] | ||
+ | [[Category: Transferase-transferase inhibitor complex]] |
Revision as of 18:13, 19 June 2013
Crystal structure of branched-chain alpha-ketoacid dehydrogenase kinase/(R)-alpha-chloroisocaproate complex with ADP
Function
[BCKD_RAT] Catalyzes the phosphorylation and inactivation of the branched-chain alpha-ketoacid dehydrogenase complex, the key regulatory enzyme of the valine, leucine and isoleucine catabolic pathways. Key enzyme that regulate the activity state of the BCKD complex.
About this Structure
4h85 is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Categories: Rattus norvegicus | Chuang, D T. | Chuang, J L. | Gui, W J. | Li, J. | Tso, S C. | Wynn, R M. | Allosteric kinase inhibitor | Bergerat nucleotide-binding fold | Branched-chain alpha-ketoacid | Branched-chain amino acid | Diabetes and obesity | Ghkl protein kinase | Maple syrup urine disease | Protein kinase | Transferase-transferase inhibitor complex