4br1
From Proteopedia
(New page: {{STRUCTURE_4br1| PDB=4br1 | SCENE= }} ===Protease-induced heterodimer of human triosephosphate isomerase.=== ==Disease== http://www.uniprot.org/uniprot/TPIS_HUMAN TPIS_HUMAN Def...) |
m (Protected "4br1" [edit=sysop:move=sysop]) |
Revision as of 21:02, 19 June 2013
Protease-induced heterodimer of human triosephosphate isomerase.
Disease
[TPIS_HUMAN] Defects in TPI1 are the cause of triosephosphate isomerase deficiency (TPI deficiency) [MIM:190450]. TPI deficiency is an autosomal recessive disorder. It is the most severe clinical disorder of glycolysis. It is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection.
About this Structure
4br1 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Categories: Homo sapiens | Triose-phosphate isomerase | Castillo-Villanueva, A. | DeLaMora-DeLaMora, I. | Enriquez-Flores, S. | Garcia-Torres, I. | Gomez-Manzo, S. | Hernandez-Alcantara, G. | Lopez-Velazquez, G. | Marcial-Quino, J. | Mendez, S T. | Mendoza-Hernandez, G. | Oria-Hernandez, J. | Reyes-Vivas, H. | Torres-Arroyo, A. | Torres-Larios, A. | Hydrolase | Protease degradation
