4fbt
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4fbt| PDB=4fbt | SCENE= }} | |
| + | ===Dpo4 post-insertion complex with the N-(deoxyguanosin-8-yl)-1-aminopyrene lesion=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/DPO4_SULSO DPO4_SULSO]] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.[HAMAP-Rule:MF_01113] | ||
| - | + | ==About this Structure== | |
| - | + | [[4fbt]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus_p2 Sulfolobus solfataricus p2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FBT OCA]. | |
| - | + | [[Category: DNA-directed DNA polymerase]] | |
| + | [[Category: Sulfolobus solfataricus p2]] | ||
| + | [[Category: Kirouac, K.]] | ||
| + | [[Category: Ling, H.]] | ||
| + | [[Category: Dna polymerase]] | ||
| + | [[Category: Transferase-dna complex]] | ||
Revision as of 21:02, 19 June 2013
Dpo4 post-insertion complex with the N-(deoxyguanosin-8-yl)-1-aminopyrene lesion
Function
[DPO4_SULSO] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.[HAMAP-Rule:MF_01113]
About this Structure
4fbt is a 3 chain structure with sequence from Sulfolobus solfataricus p2. Full crystallographic information is available from OCA.
