3lw2
From Proteopedia
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| - | [[Image:3lw2.png|left|200px]] | ||
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{{STRUCTURE_3lw2| PDB=3lw2 | SCENE= }} | {{STRUCTURE_3lw2| PDB=3lw2 | SCENE= }} | ||
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===Mouse Plasminogen Activator Inhibitor-1 (PAI-1)=== | ===Mouse Plasminogen Activator Inhibitor-1 (PAI-1)=== | ||
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{{ABSTRACT_PUBMED_20230900}} | {{ABSTRACT_PUBMED_20230900}} | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/PAI1_MOUSE PAI1_MOUSE]] Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[3lw2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LW2 OCA]. | [[3lw2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LW2 OCA]. | ||
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| - | ==See Also== | ||
| - | *[[Plasminogen activator inhibitor|Plasminogen activator inhibitor]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:020230900</ref><references group="xtra"/> | + | <ref group="xtra">PMID:020230900</ref><references group="xtra"/><references/> |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Compernolle, G.]] | [[Category: Compernolle, G.]] | ||
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[[Category: Hydrolase inhibitor]] | [[Category: Hydrolase inhibitor]] | ||
[[Category: Plasminogen activation]] | [[Category: Plasminogen activation]] | ||
| - | [[Category: Protease inhibitor]] | ||
| - | [[Category: Secreted]] | ||
| - | [[Category: Serine protease inhibitor]] | ||
Revision as of 07:34, 20 June 2013
Contents |
Mouse Plasminogen Activator Inhibitor-1 (PAI-1)
Template:ABSTRACT PUBMED 20230900
Function
[PAI1_MOUSE] Serine protease inhibitor. This inhibitor acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis (By similarity).
About this Structure
3lw2 is a 1 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Dewilde M, Van De Craen B, Compernolle G, Madsen JB, Strelkov S, Gils A, Declerck PJ. Subtle structural differences between human and mouse PAI-1 reveal the basis for biochemical differences. J Struct Biol. 2010 Mar 15. PMID:20230900 doi:10.1016/j.jsb.2010.03.006
