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4g59

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[[Image:4g59.jpg|left|200px]]
 
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{{STRUCTURE_4g59| PDB=4g59 | SCENE= }}
{{STRUCTURE_4g59| PDB=4g59 | SCENE= }}
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===Crystal structure of the murine cytomegalovirus MHC-I homolog m152 with ligand RAE-1 gamma===
===Crystal structure of the murine cytomegalovirus MHC-I homolog m152 with ligand RAE-1 gamma===
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{{ABSTRACT_PUBMED_23169621}}
{{ABSTRACT_PUBMED_23169621}}
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==Function==
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[[http://www.uniprot.org/uniprot/RAE1C_MOUSE RAE1C_MOUSE]] Acts as a ligand for NKG2D.<ref>PMID:10894171</ref>
==About this Structure==
==About this Structure==
[[4g59]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Murid_herpesvirus_1 Murid herpesvirus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G59 OCA].
[[4g59]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Murid_herpesvirus_1 Murid herpesvirus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4G59 OCA].
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==Reference==
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<ref group="xtra">PMID:023169621</ref><references group="xtra"/><references/>
[[Category: Murid herpesvirus 1]]
[[Category: Murid herpesvirus 1]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]

Revision as of 07:45, 20 June 2013

Template:STRUCTURE 4g59

Contents

Crystal structure of the murine cytomegalovirus MHC-I homolog m152 with ligand RAE-1 gamma

Template:ABSTRACT PUBMED 23169621

Function

[RAE1C_MOUSE] Acts as a ligand for NKG2D.[1]

About this Structure

4g59 is a 4 chain structure with sequence from Murid herpesvirus 1 and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Wang R, Natarajan K, Revilleza MJ, Boyd LF, Zhi L, Zhao H, Robinson H, Margulies DH. Structural basis of mouse cytomegalovirus m152/gp40 interaction with RAE1gamma reveals a paradigm for MHC/MHC interaction in immune evasion. Proc Natl Acad Sci U S A. 2012 Nov 19. PMID:23169621 doi:10.1073/pnas.1214088109
  1. Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity. 2000 Jun;12(6):721-7. PMID:10894171

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