Clp Protease
From Proteopedia
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[[1y7o]] – CLP – ''Streptococcus pneumoniae''<br /> | [[1y7o]] – CLP – ''Streptococcus pneumoniae''<br /> | ||
[[1tg6]] - CLP – human<br /> | [[1tg6]] - CLP – human<br /> | ||
| - | [[2f6i]] - CLP – ''Plasmodium falciparum''<br /> | + | [[2f6i]], [[4gm2]], [[4hnk]] - CLP – ''Plasmodium falciparum''<br /> |
[[2cby]], [[2ce3]], [[2c8t]] - CLP – ''Mycobacterium tuberculosis''<br /> | [[2cby]], [[2ce3]], [[2c8t]] - CLP – ''Mycobacterium tuberculosis''<br /> | ||
[[3fes]] - CLP – ''Clostridium difficile''<br /> | [[3fes]] - CLP – ''Clostridium difficile''<br /> | ||
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[[3p2l]] - CLP – ''Francisella tulerensis''<br /> | [[3p2l]] - CLP – ''Francisella tulerensis''<br /> | ||
[[3q7h]] - CLP – ''Coxiella burnetii''<br /> | [[3q7h]] - CLP – ''Coxiella burnetii''<br /> | ||
| - | [[3qwd]], [[3st9]], [[3sta]], [[3v5e]] - SaCLP – ''Staphylococcus aureus''<br /> | + | [[3qwd]], [[3st9]], [[3sta]], [[3v5e]], [[4emm]] - SaCLP – ''Staphylococcus aureus''<br /> |
| - | [[3v5i]] - SaCLP (mutant)<br /> | + | [[3v5i]], [[4emp]] - SaCLP (mutant)<br /> |
[[2zl0]] - HpCLP – ''Helicobacter pylori''<br /> | [[2zl0]] - HpCLP – ''Helicobacter pylori''<br /> | ||
[[2zl3]] - HpCLP (mutant)<br /> | [[2zl3]] - HpCLP (mutant)<br /> | ||
Revision as of 06:27, 25 June 2013
Clp protease (CLP) is a serine peptidase which hydrolyzes proteins in the presence of ATP and Mg+2 ion. CLP is found in mitochondria. CLP participates in degradation of misfolded proteins. CLP is a heterodimer containing an ATP-binding regulatory subunit A and catalytic subunit P. For more details see Clp protease.
3D structures of Clp protease
Updated on 25-June-2013
CLP P subunit
1tyf, 1yg6 – EcCLP – Escherichia coli
1yg8, 3hln - EcCLP (mutant)
1y7o – CLP – Streptococcus pneumoniae
1tg6 - CLP – human
2f6i, 4gm2, 4hnk - CLP – Plasmodium falciparum
2cby, 2ce3, 2c8t - CLP – Mycobacterium tuberculosis
3fes - CLP – Clostridium difficile
3ktg, 3kth, 3tt6 – BsCLP – Bacillus subtilis
3p2l - CLP – Francisella tulerensis
3q7h - CLP – Coxiella burnetii
3qwd, 3st9, 3sta, 3v5e, 4emm - SaCLP – Staphylococcus aureus
3v5i, 4emp - SaCLP (mutant)
2zl0 - HpCLP – Helicobacter pylori
2zl3 - HpCLP (mutant)
CLP P subunit binary complex
2fzs, 3mt6 - EcCLP + peptide
2zl2 - HpCLP + peptide
2zl4 - HpCLP (mutant) + peptide
3kti, 3ktj, 3ktk - BsCLP + peptide
3tt7 - BsCLP + DFP
CLP A subunit
1k6k, 1r6c – EcCLP N terminal
1ovx - EcCLP N terminal - NMR
1ksf, 1r6b – EcCLP (mutant)
1um8 – HpCLP
CLP A subunit binary complex
1lzw, 1mg9, 1mbu, 1mbv, 1mbx – EcCLP + CLP adaptor protein ClpS
1r6o, 1r6q - EcCLP N terminal + CLP adaptor protein ClpS
