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3v00

From Proteopedia

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[[Image:3v00.jpg|left|200px]]
 
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{{STRUCTURE_3v00| PDB=3v00 | SCENE= }}
{{STRUCTURE_3v00| PDB=3v00 | SCENE= }}
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===Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.===
===Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.===
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{{ABSTRACT_PUBMED_22448927}}
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==Function==
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[[http://www.uniprot.org/uniprot/GNAT1_BOVIN GNAT1_BOVIN]] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
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{{ABSTRACT_PUBMED_22448927}}
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==About this Structure==
==About this Structure==
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[[3v00]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus,_rattus_norvegicus Bos taurus, rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V00 OCA].
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[[3v00]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V00 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:022448927</ref><references group="xtra"/>
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<ref group="xtra">PMID:022448927</ref><references group="xtra"/><references/>
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[[Category: Bos taurus, rattus norvegicus]]
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[[Category: Bos taurus]]
[[Category: Cerione, R A.]]
[[Category: Cerione, R A.]]
[[Category: Singh, G.]]
[[Category: Singh, G.]]

Revision as of 07:04, 30 June 2013

Template:STRUCTURE 3v00

Contents

Studies of a constitutively active G-alpha subunit provide insights into the mechanism of G protein activation.

Template:ABSTRACT PUBMED 22448927

Function

[GNAT1_BOVIN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.

About this Structure

3v00 is a 3 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Singh G, Ramachandran S, Cerione RA. A constitutively active galpha subunit provides insights into the mechanism of g protein activation. Biochemistry. 2012 Apr 17;51(15):3232-40. Epub 2012 Apr 5. PMID:22448927 doi:10.1021/bi3001984

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