4gx9

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==About this Structure==
==About this Structure==
[[4gx9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GX9 OCA].
[[4gx9]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GX9 OCA].
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==Reference==
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<ref group="xtra">PMID:023580545</ref><references group="xtra"/><references/>
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Dixon, N E.]]
[[Category: Dixon, N E.]]

Revision as of 07:19, 30 June 2013

Template:STRUCTURE 4gx9

Contents

Crystal structure of a DNA polymerase III alpha-epsilon chimera

Template:ABSTRACT PUBMED 23580545

Function

[DPO3E_ECOLI] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease.

About this Structure

4gx9 is a 4 chain structure. Full crystallographic information is available from OCA.

Reference

  • Ozawa K, Horan NP, Robinson A, Yagi H, Hill FR, Jergic S, Xu ZQ, Loscha KV, Li N, Tehei M, Oakley AJ, Otting G, Huber T, Dixon NE. Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits alpha, {varepsilon}, theta and beta reveals a highly flexible arrangement of the proofreading domain. Nucleic Acids Res. 2013 Apr 10. PMID:23580545 doi:10.1093/nar/gkt162

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