3vmx
From Proteopedia
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{{STRUCTURE_3vmx| PDB=3vmx | SCENE= }} | {{STRUCTURE_3vmx| PDB=3vmx | SCENE= }} | ||
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===Crystal Structure of a parallel coiled-coil dimerization domain from the voltage-gated proton channel=== | ===Crystal Structure of a parallel coiled-coil dimerization domain from the voltage-gated proton channel=== | ||
| + | {{ABSTRACT_PUBMED_22569364}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/HVCN1_MOUSE HVCN1_MOUSE]] Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[3vmx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMX OCA]. | [[3vmx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VMX OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022569364</ref><references group="xtra"/><references/> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Fujiwara, Y.]] | [[Category: Fujiwara, Y.]] | ||
Revision as of 07:29, 30 June 2013
Contents |
Crystal Structure of a parallel coiled-coil dimerization domain from the voltage-gated proton channel
Template:ABSTRACT PUBMED 22569364
Function
[HVCN1_MOUSE] Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis (By similarity).
About this Structure
3vmx is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Fujiwara Y, Kurokawa T, Takeshita K, Kobayashi M, Okochi Y, Nakagawa A, Okamura Y. The cytoplasmic coiled-coil mediates cooperative gating temperature sensitivity in the voltage-gated H(+) channel Hv1. Nat Commun. 2012 May 8;3:816. doi: 10.1038/ncomms1823. PMID:22569364 doi:10.1038/ncomms1823
