4def
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:4def.jpg|left|200px]] | ||
| - | |||
{{STRUCTURE_4def| PDB=4def | SCENE= }} | {{STRUCTURE_4def| PDB=4def | SCENE= }} | ||
| - | |||
===Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis=== | ===Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis=== | ||
| - | |||
{{ABSTRACT_PUBMED_23298222}} | {{ABSTRACT_PUBMED_23298222}} | ||
| + | |||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/ALF_MYCTU ALF_MYCTU]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[4def]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEF OCA]. | [[4def]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEF OCA]. | ||
| + | |||
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:023298222</ref><references group="xtra"/><references/> | ||
[[Category: Fructose-bisphosphate aldolase]] | [[Category: Fructose-bisphosphate aldolase]] | ||
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
Revision as of 07:38, 30 June 2013
Contents |
Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis
Template:ABSTRACT PUBMED 23298222
Function
[ALF_MYCTU] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).
About this Structure
4def is a 1 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Pegan SD, Rukseree K, Capodagli GC, Baker EA, Krasnykh O, Franzblau SG, Mesecar AD. Active Site Loop Dynamics of a Class IIa Fructose 1,6-Bisphosphate Aldolase from Mycobacterium tuberculosis. Biochemistry. 2013 Jan 18. PMID:23298222 doi:10.1021/bi300928u
