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4dcn
From Proteopedia
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{{STRUCTURE_4dcn| PDB=4dcn | SCENE= }} | {{STRUCTURE_4dcn| PDB=4dcn | SCENE= }} | ||
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===Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1=== | ===Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1=== | ||
| + | {{ABSTRACT_PUBMED_22679020}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/ARL1_HUMAN ARL1_HUMAN]] GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus.<ref>PMID:9624189</ref> [[http://www.uniprot.org/uniprot/ARFP2_HUMAN ARFP2_HUMAN]] Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling. | ||
==About this Structure== | ==About this Structure== | ||
[[4dcn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DCN OCA]. | [[4dcn]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DCN OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022679020</ref><references group="xtra"/><references/> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Kato, R.]] | [[Category: Kato, R.]] | ||
Revision as of 07:59, 30 June 2013
Contents |
Crystal Structure Analysis of the Arfaptin2 BAR domain in Complex with ARL1
Template:ABSTRACT PUBMED 22679020
Function
[ARL1_HUMAN] GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus.[1] [ARFP2_HUMAN] Putative target protein of ADP-ribosylation factor. Involved in membrane ruffling.
About this Structure
4dcn is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Nakamura K, Man Z, Xie Y, Hanai A, Makyio H, Kawasaki M, Kato R, Shin HW, Nakayama K, Wakatsuki S. Structural basis for membrane binding specificity of the Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin-2 determined by Arl1 GTPase. J Biol Chem. 2012 Jul 20;287(30):25478-89. doi: 10.1074/jbc.M112.365783. Epub, 2012 Jun 7. PMID:22679020 doi:10.1074/jbc.M112.365783
