2huw
From Proteopedia
(New page: 200px<br /> <applet load="2huw" size="450" color="white" frame="true" align="right" spinBox="true" caption="2huw, resolution 1.900Å" /> '''X-ray crystal stru...) |
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| - | [[Image:2huw.gif|left|200px]]<br /> | + | [[Image:2huw.gif|left|200px]]<br /><applet load="2huw" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2huw" size=" | + | |
caption="2huw, resolution 1.900Å" /> | caption="2huw, resolution 1.900Å" /> | ||
'''X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand'''<br /> | '''X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2HUW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with PO4 and YVN as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http:// | + | 2HUW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PO4:'>PO4</scene> and <scene name='pdbligand=YVN:'>YVN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HUW OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Benfield, A | + | [[Category: Benfield, A P.]] |
| - | [[Category: Martin, S | + | [[Category: Martin, S F.]] |
[[Category: PO4]] | [[Category: PO4]] | ||
[[Category: YVN]] | [[Category: YVN]] | ||
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[[Category: sh2]] | [[Category: sh2]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:46:02 2008'' |
Revision as of 15:46, 21 February 2008
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X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand
Disease
Known diseases associated with this structure: Central hypoventilation syndrome, congenital OMIM:[100790], Haddad syndrome OMIM:[100790]
About this Structure
2HUW is a Single protein structure of sequence from Homo sapiens with and as ligands. Full crystallographic information is available from OCA.
Reference
Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions., Benfield AP, Teresk MG, Plake HR, DeLorbe JE, Millspaugh LE, Martin SF, Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6830-5. PMID:17001728
Page seeded by OCA on Thu Feb 21 17:46:02 2008
Categories: Homo sapiens | Single protein | Benfield, A P. | Martin, S F. | PO4 | YVN | Contrained | Cylcopropane | Grb2 | Preorganization | Sh2
