2huy

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(New page: 200px<br /> <applet load="2huy" size="450" color="white" frame="true" align="right" spinBox="true" caption="2huy, resolution 1.700&Aring;" /> '''X-ray crystal stru...)
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[[Image:2huy.gif|left|200px]]<br />
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[[Image:2huy.gif|left|200px]]<br /><applet load="2huy" size="350" color="white" frame="true" align="right" spinBox="true"
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<applet load="2huy" size="450" color="white" frame="true" align="right" spinBox="true"
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caption="2huy, resolution 1.700&Aring;" />
caption="2huy, resolution 1.700&Aring;" />
'''X-ray crystal structure of the complex between the Grb2-SH2 domain and a flexible ligand, fpYVN.'''<br />
'''X-ray crystal structure of the complex between the Grb2-SH2 domain and a flexible ligand, fpYVN.'''<br />
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==About this Structure==
==About this Structure==
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2HUY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with YVN and FMT as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=2HUY OCA].
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2HUY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=YVN:'>YVN</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HUY OCA].
==Reference==
==Reference==
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Benfield, A.P.]]
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[[Category: Benfield, A P.]]
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[[Category: Martin, S.F.]]
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[[Category: Martin, S F.]]
[[Category: FMT]]
[[Category: FMT]]
[[Category: YVN]]
[[Category: YVN]]
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[[Category: ligand preorganization]]
[[Category: ligand preorganization]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 12 22:36:34 2007''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:46:06 2008''

Revision as of 15:46, 21 February 2008


2huy, resolution 1.700Å

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X-ray crystal structure of the complex between the Grb2-SH2 domain and a flexible ligand, fpYVN.

Disease

Known diseases associated with this structure: Central hypoventilation syndrome, congenital OMIM:[100790], Haddad syndrome OMIM:[100790]

About this Structure

2HUY is a Single protein structure of sequence from Homo sapiens with and as ligands. Full crystallographic information is available from OCA.

Reference

Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions., Benfield AP, Teresk MG, Plake HR, DeLorbe JE, Millspaugh LE, Martin SF, Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6830-5. PMID:17001728

Page seeded by OCA on Thu Feb 21 17:46:06 2008

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