3va3

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[[Image:3va3.jpg|left|200px]]
 
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{{STRUCTURE_3va3| PDB=3va3 | SCENE= }}
{{STRUCTURE_3va3| PDB=3va3 | SCENE= }}
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===Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)===
===Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)===
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{{ABSTRACT_PUBMED_22718982}}
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{{ABSTRACT_PUBMED_22718982}}
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==Function==
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[[http://www.uniprot.org/uniprot/RNT_ECOLI RNT_ECOLI]] Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis, especially in strains lacking other exoribonucleases.[HAMAP-Rule:MF_00157]
==About this Structure==
==About this Structure==
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[[3va3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VA3 OCA].
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[[3va3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VA3 OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:022718982</ref><references group="xtra"/>
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<ref group="xtra">PMID:022718982</ref><references group="xtra"/><references/>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli k-12]]
[[Category: Hsiao, Y Y.]]
[[Category: Hsiao, Y Y.]]
[[Category: Yuan, H S.]]
[[Category: Yuan, H S.]]

Revision as of 08:13, 30 June 2013

Template:STRUCTURE 3va3

Contents

Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)

Template:ABSTRACT PUBMED 22718982

Function

[RNT_ECOLI] Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis, especially in strains lacking other exoribonucleases.[HAMAP-Rule:MF_00157]

About this Structure

3va3 is a 4 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

  • Hsiao YY, Duh Y, Chen YP, Wang YT, Yuan HS. How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes. Nucleic Acids Res. 2012 Jun 19. PMID:22718982 doi:10.1093/nar/gks548

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OCA

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