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3va3
From Proteopedia
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| - | [[Image:3va3.jpg|left|200px]] | ||
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{{STRUCTURE_3va3| PDB=3va3 | SCENE= }} | {{STRUCTURE_3va3| PDB=3va3 | SCENE= }} | ||
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===Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)=== | ===Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)=== | ||
| + | {{ABSTRACT_PUBMED_22718982}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/RNT_ECOLI RNT_ECOLI]] Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis, especially in strains lacking other exoribonucleases.[HAMAP-Rule:MF_00157] | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3va3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3va3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VA3 OCA]. |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID:022718982</ref><references group="xtra"/> | + | <ref group="xtra">PMID:022718982</ref><references group="xtra"/><references/> |
| - | [[Category: Escherichia coli]] | + | [[Category: Escherichia coli k-12]] |
[[Category: Hsiao, Y Y.]] | [[Category: Hsiao, Y Y.]] | ||
[[Category: Yuan, H S.]] | [[Category: Yuan, H S.]] | ||
Revision as of 08:13, 30 June 2013
Contents |
Crystal structure of RNase T in complex with a duplex DNA product (stem loop DNA with 2 nucleotide 3' overhang)
Template:ABSTRACT PUBMED 22718982
Function
[RNT_ECOLI] Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis, especially in strains lacking other exoribonucleases.[HAMAP-Rule:MF_00157]
About this Structure
3va3 is a 4 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Hsiao YY, Duh Y, Chen YP, Wang YT, Yuan HS. How an exonuclease decides where to stop in trimming of nucleic acids: crystal structures of RNase T-product complexes. Nucleic Acids Res. 2012 Jun 19. PMID:22718982 doi:10.1093/nar/gks548
