2l2z
From Proteopedia
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{{STRUCTURE_2l2z| PDB=2l2z | SCENE= }} | {{STRUCTURE_2l2z| PDB=2l2z | SCENE= }} | ||
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===Thiostrepton, reduced at N-CA bond of residue 14=== | ===Thiostrepton, reduced at N-CA bond of residue 14=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/THCL_STRAJ THCL_STRAJ]] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
[[2l2z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2Z OCA]. | [[2l2z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_azureus Streptomyces azureus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L2Z OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021365717</ref><references group="xtra"/><references/> | ||
[[Category: Streptomyces azureus]] | [[Category: Streptomyces azureus]] | ||
[[Category: Arndt, H D.]] | [[Category: Arndt, H D.]] | ||
Revision as of 08:14, 30 June 2013
Contents |
Thiostrepton, reduced at N-CA bond of residue 14
Function
[THCL_STRAJ] Has bacteriocidal activity. Inhibits bacterial protein biosynthesis by acting on the elongation factor Tu (EF-Tu) (By similarity).
About this Structure
2l2z is a 1 chain structure with sequence from Streptomyces azureus. Full experimental information is available from OCA.
Reference
- Jonker HR, Baumann S, Wolf A, Schoof S, Hiller F, Schulte KW, Kirschner KN, Schwalbe H, Arndt HD. NMR structures of thiostrepton derivatives for characterization of the ribosomal binding site. Angew Chem Int Ed Engl. 2011 Mar 28;50(14):3308-12. doi: 10.1002/anie.201003582. , Epub 2011 Mar 1. PMID:21365717 doi:10.1002/anie.201003582
