2hvp
From Proteopedia
(New page: 200px<br /> <applet load="2hvp" size="450" color="white" frame="true" align="right" spinBox="true" caption="2hvp, resolution 3.0Å" /> '''THREE-DIMENSIONAL ST...) |
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| - | [[Image:2hvp.gif|left|200px]]<br /> | + | [[Image:2hvp.gif|left|200px]]<br /><applet load="2hvp" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2hvp" size=" | + | |
caption="2hvp, resolution 3.0Å" /> | caption="2hvp, resolution 3.0Å" /> | ||
'''THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1'''<br /> | '''THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The crystal structure of the protease of the human immunodeficiency virus | + | The crystal structure of the protease of the human immunodeficiency virus type (HIV-1), which releases structural proteins and enzymes from viral polyprotein products, has been determined to 3 A resolution. Large regions of the protease dimer, including the active site, have structural homology to the family of microbial aspartyl proteases. The structure suggests a mechanism for the autoproteolytic release of protease and a role in the control of virus maturation. |
==About this Structure== | ==About this Structure== | ||
| - | 2HVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http:// | + | 2HVP is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HVP OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Fitzgerald, P | + | [[Category: Fitzgerald, P M.D.]] |
| - | [[Category: Mckeever, B | + | [[Category: Mckeever, B M.]] |
| - | [[Category: Navia, M | + | [[Category: Navia, M A.]] |
| - | [[Category: Springer, J | + | [[Category: Springer, J P.]] |
[[Category: hydrolase(acid proteinase)]] | [[Category: hydrolase(acid proteinase)]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:46:14 2008'' |
Revision as of 15:46, 21 February 2008
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THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1
Overview
The crystal structure of the protease of the human immunodeficiency virus type (HIV-1), which releases structural proteins and enzymes from viral polyprotein products, has been determined to 3 A resolution. Large regions of the protease dimer, including the active site, have structural homology to the family of microbial aspartyl proteases. The structure suggests a mechanism for the autoproteolytic release of protease and a role in the control of virus maturation.
About this Structure
2HVP is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.
Reference
Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1., Navia MA, Fitzgerald PM, McKeever BM, Leu CT, Heimbach JC, Herber WK, Sigal IS, Darke PL, Springer JP, Nature. 1989 Feb 16;337(6208):615-20. PMID:2645523
Page seeded by OCA on Thu Feb 21 17:46:14 2008
