3uit
From Proteopedia
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{{STRUCTURE_3uit| PDB=3uit | SCENE= }} | {{STRUCTURE_3uit| PDB=3uit | SCENE= }} | ||
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===Overall structure of Patj/Pals1/Mals complex=== | ===Overall structure of Patj/Pals1/Mals complex=== | ||
| + | {{ABSTRACT_PUBMED_22337881}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/INADL_MOUSE INADL_MOUSE]] Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.<ref>PMID:11872753</ref> | ||
==About this Structure== | ==About this Structure== | ||
| - | [[3uit]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[3uit]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UIT OCA]. |
| - | [[Category: | + | |
| + | ==Reference== | ||
| + | <ref group="xtra">PMID:022337881</ref><references group="xtra"/><references/> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Long, J.]] | [[Category: Long, J.]] | ||
[[Category: Shen, Y.]] | [[Category: Shen, Y.]] | ||
Revision as of 09:44, 3 July 2013
Contents |
Overall structure of Patj/Pals1/Mals complex
Template:ABSTRACT PUBMED 22337881
Function
[INADL_MOUSE] Scaffolding protein that may bring different proteins into adjacent positions at the cell membrane. May regulate protein targeting, cell polarity and integrity of tight junctions. May regulate the surface expression and/or function of ASIC3 in sensory neurons.[1]
About this Structure
3uit is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Zhang J, Yang X, Wang Z, Zhou H, Xie X, Shen Y, Long J. Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode. J Biol Chem. 2012 Mar 30;287(14):11132-40. Epub 2012 Feb 15. PMID:22337881 doi:10.1074/jbc.M111.321216
- ↑ Anzai N, Deval E, Schaefer L, Friend V, Lazdunski M, Lingueglia E. The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons. J Biol Chem. 2002 May 10;277(19):16655-61. Epub 2002 Feb 28. PMID:11872753 doi:10.1074/jbc.M201087200
