4elx
From Proteopedia
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{{STRUCTURE_4elx| PDB=4elx | SCENE= }} | {{STRUCTURE_4elx| PDB=4elx | SCENE= }} | ||
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===Structure of apo E.coli. 1,4-dihydroxy-2- naphthoyl CoA synthases with Cl=== | ===Structure of apo E.coli. 1,4-dihydroxy-2- naphthoyl CoA synthases with Cl=== | ||
+ | {{ABSTRACT_PUBMED_22606952}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/MENB_ECOLI MENB_ECOLI]] Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).<ref>PMID:1091286</ref> <ref>PMID:20643650</ref> | |
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==About this Structure== | ==About this Structure== | ||
- | [[4elx]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/ | + | [[4elx]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ELX OCA]. |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID:022606952</ref><references group="xtra"/> | + | <ref group="xtra">PMID:022606952</ref><references group="xtra"/><references/> |
- | [[Category: | + | [[Category: 1,4-dihydroxy-2-naphthoyl-CoA synthase]] |
- | [[Category: | + | [[Category: Escherichia coli k-12]] |
[[Category: Guo, Z H.]] | [[Category: Guo, Z H.]] | ||
[[Category: Jiang, M.]] | [[Category: Jiang, M.]] |
Revision as of 11:19, 3 July 2013
Contents |
Structure of apo E.coli. 1,4-dihydroxy-2- naphthoyl CoA synthases with Cl
Template:ABSTRACT PUBMED 22606952
Function
[MENB_ECOLI] Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).[1] [2]
About this Structure
4elx is a 6 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Sun Y, Song H, Li J, Jiang M, Li Y, Zhou J, Guo Z. Active Site Binding and Catalytic Role of Bicarbonate in 1,4-Dihydroxy-2-naphthoyl Coenzyme A Synthases from Vitamin K Biosynthetic Pathways. Biochemistry. 2012 May 24. PMID:22606952 doi:10.1021/bi300486j
- ↑ Young IG. Biosynthesis of bacterial menaquinones. Menaquinone mutants of Escherichia coli. Biochemistry. 1975 Jan 28;14(2):399-406. PMID:1091286
- ↑ Jiang M, Chen M, Guo ZF, Guo Z. A bicarbonate cofactor modulates 1,4-dihydroxy-2-naphthoyl-coenzyme a synthase in menaquinone biosynthesis of Escherichia coli. J Biol Chem. 2010 Sep 24;285(39):30159-69. doi: 10.1074/jbc.M110.147702. Epub, 2010 Jul 19. PMID:20643650 doi:10.1074/jbc.M110.147702