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3vkm

From Proteopedia

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[[Image:3vkm.jpg|left|200px]]
 
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{{STRUCTURE_3vkm| PDB=3vkm | SCENE= }}
{{STRUCTURE_3vkm| PDB=3vkm | SCENE= }}
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===Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose===
===Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose===
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{{ABSTRACT_PUBMED_22913484}}
{{ABSTRACT_PUBMED_22913484}}
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==Function==
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[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref>
==About this Structure==
==About this Structure==
[[3vkm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VKM OCA].
[[3vkm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VKM OCA].
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==Reference==
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<ref group="xtra">PMID:022913484</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kamitori, S.]]
[[Category: Kamitori, S.]]

Revision as of 12:36, 3 July 2013

Template:STRUCTURE 3vkm

Contents

Protease-resistant mutant form of Human Galectin-8 in complex with sialyllactose and lactose

Template:ABSTRACT PUBMED 22913484

Function

[LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.[1]

About this Structure

3vkm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yoshida H, Yamashita S, Teraoka M, Itoh A, Nakakita SI, Nishi N, Kamitori S. X-ray Structure of a Protease-resistant Mutant Form of Human Galectin-8 with Two Carbohydrate Recognition Domains. FEBS J. 2012 Aug 22. doi: 10.1111/j.1742-4658.2012.08753.x. PMID:22913484 doi:10.1111/j.1742-4658.2012.08753.x
  1. Ideo H, Matsuzaka T, Nonaka T, Seko A, Yamashita K. Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans. J Biol Chem. 2011 Apr 1;286(13):11346-55. Epub 2011 Feb 2. PMID:21288902 doi:10.1074/jbc.M110.195925

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