4da1
From Proteopedia
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==About this Structure== | ==About this Structure== | ||
[[4da1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DA1 OCA]. | [[4da1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DA1 OCA]. | ||
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| + | ==See Also== | ||
| + | *[[Protein phosphatase|Protein phosphatase]] | ||
==Reference== | ==Reference== | ||
Revision as of 14:01, 3 July 2013
Contents |
Crystal structure of branched-chain alpha-ketoacid dehydrogenase phosphatase with Mg (II) ions at the active site
Template:ABSTRACT PUBMED 22291014
Disease
[PPM1K_HUMAN] Intermediate maple syrup urine disease.
Function
[PPM1K_HUMAN] Regulates the mitochondrial permeability transition pore and is essential for cellular survival and development.[1]
About this Structure
4da1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Wynn RM, Li J, Brautigam CA, Chuang JL, Chuang DT. Structural and biochemical characterization of human mitochondrial branched-chain alpha-ketoacid dehydrogenase phosphatase. J Biol Chem. 2012 Mar 16;287(12):9178-92. Epub 2012 Jan 30. PMID:22291014 doi:10.1074/jbc.M111.314963
- ↑ Lu G, Ren S, Korge P, Choi J, Dong Y, Weiss J, Koehler C, Chen JN, Wang Y. A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development. Genes Dev. 2007 Apr 1;21(7):784-96. Epub 2007 Mar 20. PMID:17374715 doi:http://dx.doi.org/10.1101/gad.1499107
