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4bh5
From Proteopedia
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| - | + | {{STRUCTURE_4bh5| PDB=4bh5 | SCENE= }} | |
| + | ===LytM domain of EnvC, an activator of cell wall amidases in Escherichia coli=== | ||
| + | {{ABSTRACT_PUBMED_23796240}} | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/ENVC_ECOLI ENVC_ECOLI]] Activator of the cell wall hydrolases AmiA and AmiB. Required for septal murein cleavage and daughter cell separation during cell division. In vitro, exhibits weak endoproteolytic activity on beta-casein.<ref>PMID:11976287</ref> <ref>PMID:15165230</ref> <ref>PMID:19525345</ref> <ref>PMID:20300061</ref> | ||
| - | + | ==About this Structure== | |
| + | [[4bh5]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BH5 OCA]. | ||
| - | + | ==Reference== | |
| + | <ref group="xtra">PMID:023796240</ref><references group="xtra"/><references/> | ||
| + | [[Category: Escherichia coli k-12]] | ||
| + | [[Category: Bernhardt, T G.]] | ||
| + | [[Category: Morlot, C.]] | ||
| + | [[Category: Peters, N T.]] | ||
| + | [[Category: Uehara, T.]] | ||
| + | [[Category: Vernet, T.]] | ||
| + | [[Category: Yang, D C.]] | ||
| + | [[Category: Amidase activator]] | ||
| + | [[Category: Autolysin]] | ||
| + | [[Category: Cell cycle]] | ||
| + | [[Category: Cytokinesis]] | ||
| + | [[Category: Morphogenesis]] | ||
| + | [[Category: Peptidoglycan]] | ||
| + | [[Category: Sacculus]] | ||
Revision as of 14:01, 3 July 2013
Contents |
LytM domain of EnvC, an activator of cell wall amidases in Escherichia coli
Template:ABSTRACT PUBMED 23796240
Function
[ENVC_ECOLI] Activator of the cell wall hydrolases AmiA and AmiB. Required for septal murein cleavage and daughter cell separation during cell division. In vitro, exhibits weak endoproteolytic activity on beta-casein.[1] [2] [3] [4]
About this Structure
4bh5 is a 4 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- Peters NT, Morlot C, Yang DC, Uehara T, Vernet T, Bernhardt TG. Structure-function analysis of the LytM domain of EnvC, an activator of cell wall remodeling at the Escherichia coli division site. Mol Microbiol. 2013 Jun 25. doi: 10.1111/mmi.12304. PMID:23796240 doi:10.1111/mmi.12304
- ↑ Ichimura T, Yamazoe M, Maeda M, Wada C, Hiraga S. Proteolytic activity of YibP protein in Escherichia coli. J Bacteriol. 2002 May;184(10):2595-602. PMID:11976287
- ↑ Bernhardt TG, de Boer PA. Screening for synthetic lethal mutants in Escherichia coli and identification of EnvC (YibP) as a periplasmic septal ring factor with murein hydrolase activity. Mol Microbiol. 2004 Jun;52(5):1255-69. PMID:15165230 doi:10.1111/j.1365-2958.2004.04063.x
- ↑ Uehara T, Dinh T, Bernhardt TG. LytM-domain factors are required for daughter cell separation and rapid ampicillin-induced lysis in Escherichia coli. J Bacteriol. 2009 Aug;191(16):5094-107. doi: 10.1128/JB.00505-09. Epub 2009 Jun, 12. PMID:19525345 doi:10.1128/JB.00505-09
- ↑ Uehara T, Parzych KR, Dinh T, Bernhardt TG. Daughter cell separation is controlled by cytokinetic ring-activated cell wall hydrolysis. EMBO J. 2010 Apr 21;29(8):1412-22. doi: 10.1038/emboj.2010.36. Epub 2010 Mar 18. PMID:20300061 doi:10.1038/emboj.2010.36
