2m0z

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-	'''Unreleased structure'''	+	{{STRUCTURE_2m0z| PDB=2m0z | SCENE= }}
		+	===cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative===
-	The entry 2m0z is ON HOLD until Paper Publication	+	==Function==
		+	[[http://www.uniprot.org/uniprot/PTN13_HUMAN PTN13_HUMAN]] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.<ref>PMID:15611135</ref>
-	Authors: Walser, R., Zerbe, O., Hamm, P.	+	==About this Structure==
		+	[[2m0z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0Z OCA].
-	Description: cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative	+	==Reference==
		+	<references group="xtra"/><references/>
		+	[[Category: Homo sapiens]]
		+	[[Category: Protein-tyrosine-phosphatase]]
		+	[[Category: Hamm, P.]]
		+	[[Category: Walser, R.]]
		+	[[Category: Zerbe, O.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Photoswitch]]

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Revision as of 14:11, 3 July 2013

Template:STRUCTURE 2m0z

Contents 1 cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative 2 Function 3 About this Structure 4 Reference

cis form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative

Function

[PTN13_HUMAN] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.^[1]

About this Structure

2m0z is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

Reference

1. ↑ Villa F, Deak M, Bloomberg GB, Alessi DR, van Aalten DM. Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket. J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20. PMID:15611135 doi:10.1074/jbc.M412211200