2m10
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_2m10| PDB=2m10 | SCENE= }} | |
| + | ===trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/PTN13_HUMAN PTN13_HUMAN]] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.<ref>PMID:15611135</ref> | ||
| - | + | ==About this Structure== | |
| + | [[2m10]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M10 OCA]. | ||
| - | + | ==Reference== | |
| + | <references group="xtra"/><references/> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Protein-tyrosine-phosphatase]] | ||
| + | [[Category: Walser, R.]] | ||
| + | [[Category: Hydrolase]] | ||
| + | [[Category: Photoswitch]] | ||
Revision as of 14:11, 3 July 2013
Contents |
trans form of a photoswitchable PDZ domain crosslinked with an azobenzene derivative
Function
[PTN13_HUMAN] Tyrosine phosphatase which regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling.[1]
About this Structure
2m10 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.
Reference
- ↑ Villa F, Deak M, Bloomberg GB, Alessi DR, van Aalten DM. Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket. J Biol Chem. 2005 Mar 4;280(9):8180-7. Epub 2004 Dec 20. PMID:15611135 doi:10.1074/jbc.M412211200
